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Clinical practice guidelines for cancer-related fatigue in China (2021 edition) [PDF]

Zhongguo aizheng zazhi, 2021
Cancer has become one of the most important public issues which seriously influence the health condition of Chinese population. The cancer-related fatigue has drawn great attention.
Tumor Support and Rehabilitation Therapy Group, the Oncology Committee of Chinese Medical Association
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Myeloid-Derived Suppressor Cells and CD68+CD163+M2-Like Macrophages as Therapeutic Response Biomarkers Are Associated with Plasma Inflammatory Cytokines: A Preliminary Study for Non-Small Cell Lung Cancer Patients in Radiotherapy

Journal of Immunology Research, 2022
Background. Recent studies show that myeloid-derived suppressor cells (MDSCs) and M2-like macrophages are involved in the treatment of tumors; however, their therapeutic response role is rarely known in non-small cell lung cancer (NSCLC) during ...
Minghe Lv, Xibing Zhuang, Shali Shao, Xuan Li, Yunfeng Cheng, Duojiao Wu, Xiangdong Wang, Tiankui Qiao   +7 more
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Membrane and Soluble CD137 in Systemic Lupus Erythematosus: Role as Biomarkers for Disease Activity

Journal of Immunology Research, 2023
Objective. The role of T cells in the pathogenesis of systemic lupus erythematosus (SLE) has recently gained attention. Costimulatory molecules are membrane proteins strictly associated with T-cell receptor (TCR), acting by activating or inhibiting T ...
Fulvia Ceccarelli, Francesco Natalucci, Alessandra Di Filippo, Giulio Olivieri, Chiara Napoletano, Aurelia Rughetti, Marianna Nuti, Ilaria Grazia Zizzari, Fabrizio Conti   +8 more
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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity

Journal for ImmunoTherapy of Cancer, 2021
Background Natural killer group 2D (NKG2D) is an activating receptor of natural killer (NK) cells and other lymphocytes that mediates lysis of malignant cells through recognition of stress-induced ligands such as MICA and MICB.
Congcong Zhang, Anja Waldmann, Winfried S Wels, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Nina Müller, Pranav Oberoi   +9 more
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Viruses for Tumor Therapy [PDF]

Cell Host & Microbe, 2014
Oncolytic virotherapy exploits live viruses with selective tropism for cancerous cells and tissues to treat cancer. As discussed here, the field has progressed considerably as a result of both the successes and failures of previous and on-going clinical trials for various cancers.
Center for Cancer Therapeutics, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada ( host institution ), Bell, John ( author ), McFadden, Grant ( author )   +2 more
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Single-cell analyses reveal the therapeutic effects of ATHENA and its mechanism in a rhabdomyosarcoma patient

Frontiers in Oncology, 2022
BackgroundWhole-cell tumor vaccines tend to suffer from low immunogenicity. Our previous study showed that irradiated lung cancer cell vaccines in mouse models enhance antitumor efficacy by eliciting an intensive T cells response and improving ...
Yujun Liu, Ke Wang, Yanli Zhou, Xibing Zhuang, Shali Shao, Fulu Qiao, Xiangdong Wang, Xin Zou, Tiankui Qiao   +8 more
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Neutrophils contribute to elevated BAFF levels to modulate adaptive immunity in patients with primary immune thrombocytopenia by CD62P and PSGL1 interaction

Clinical & Translational Immunology, 2022
Objectives Immune thrombocytopenia (ITP) is an autoimmune disease characterised by impaired platelet production and increased platelet destruction. However, the involvement of neutrophils in ITP is yet to be explored.
Pengcheng Xu, Xia Shao, Yang Ou, Yanxia Zhan, Lili Ji, Xibing Zhuang, Ying Li, Yanna Ma, Duojiao Wu, Tiankui Qiao, Xiangdong Wang, Hao Chen, Yunfeng Cheng   +12 more
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Mesenchymal stem cell therapy for liver disease: full of chances and challenges

Cell & Bioscience, 2020
Liver disease is a major health problem that endangers human health worldwide. Currently, whole organ allograft transplantation is the gold standard for the treatment of end-stage liver disease.
Xue Yang, Yan Meng, Zhipeng Han, Fei Ye, Lixin Wei, Chen Zong   +5 more
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The immune suppressive microenvironment affects efficacy of radio‐immunotherapy in brain metastasis

EMBO Molecular Medicine, 2021
The tumor microenvironment in brain metastases is characterized by high myeloid cell content associated with immune suppressive and cancer‐permissive functions. Moreover, brain metastases induce the recruitment of lymphocytes.
Katja Niesel, Michael Schulz, Julian Anthes, Tijna Alekseeva, Jadranka Macas, Anna Salamero‐Boix, Aylin Möckl, Timm Oberwahrenbrock, Marco Lolies, Stefan Stein, Karl H Plate, Yvonne Reiss, Franz Rödel, Lisa Sevenich   +13 more
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Involvement of inflammasomes in tumor microenvironment and tumor therapies

Journal of Hematology & Oncology, 2023
AbstractInflammasomes are macromolecular platforms formed in response to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns, whose formation would cause maturation of interleukin-1 (IL-1) family members and gasdermin D (GSDMD), leading to IL-1 secretion and pyroptosis respectively.
Ziqi Zhang, Xue Li, Yang Wang, Yuquan Wei, Xiawei Wei   +4 more
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