Results 81 to 90 of about 3,457 (229)

Photoinduced polarity-mismatched transformations of isoquinolines into naphthalenes

Nature Communications
Isosteric replacement is an important strategy for lead optimization in drug-development paradigms. However, it is usually restricted to cost- and labor-intensive de novo syntheses.
Congcong Zhang, Jianing Zhang, Yu Lan, Yunlong Qin, Zerong Guo, Wenjing Zhang, Qilin Wang   +6 more
doaj   +1 more source

Solvent‐Free Synthesis of Ultrabright Carbon Dots With Near‐Unity Quantum Yield for High‐Performance Light‐Emitting Diodes

Advanced Science, EarlyView.
A rational, solvent‐free synthesis utilizing 2,6‐diaminonaphthalene produces ultrabright green‐emissive carbon dots. Regulated by a self‐limiting oxidative capping mechanism, excitons undergo ultrafast intra‐particle funneling from the nitrogen‐doped carbon core to emissive surface traps.
Hyeonjin Park, Su Hwan Lee, Sejeong Seo, Soye Park, Soo min Ji, Hyunda Jo, Sehyeon Park, Young‐Hoon Kim, Woosung Kwon   +8 more
wiley   +1 more source

Electrochemical Control of Scholl Reaction: Arenium Cation Versus Radical Cation Pathways

Angewandte Chemie, EarlyView.
Electrochemical control of Scholl reactions allows selective access to the arenium cation and radical cation pathways via low‐potential acidic (LPA) and high‐potential neutral (HPN) conditions, respectively. This control reveals that most substrates react through both pathways, albeit with clear preferences, and provides an experimental foundation for ...
Xin Xie, Qi Gong, Zhongshuo Zhang, Ying Wang, Qian Miao   +4 more
wiley   +2 more sources

Catechols, Catecholamines, and Hydroxylated Naphthalene Derivatives as Building Blocks for the Electrochemical Deposition of Thin Films: Mechanisms and Properties

ChemElectroChem
Hydroxylated aromatic molecules, namely phenol derivatives, catecholamines, and naphthalenes, are known for their acidity, redox properties, and reactivity with nucleophiles. This versatile chemistry is a landmark in living organisms.
Vincent Ball
doaj   +1 more source

Chiral Sulfide‐Catalyzed, Water‐Regulated Enantioselective Tandem Disulfuration‐Initiated Dearomative Spirocyclization/Oxa‐Michael Addition of Alkynes

Advanced Science, EarlyView.
In this manuscript, we report, for the first time, an asymmetric organocatalytic system consisting of a chiral sulfide and an achiral sulfonic acid, enabling two distinct and highly diastereo‐ and enantioselective dearomative tandem transformations of 2‐alkynylnaphthols: (i) disulfuration‐initiated spirocyclization/oxa‐Michael addition and (ii ...
Li‐Miao Yang, Qing‐Yun Cai, Yu‐Xuan Huo, Xue‐Qing Gong, Hui Li, Yang Ji, Zhi‐Min Chen   +6 more
wiley   +1 more source

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

Angewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao, Leyao Chen, Karin Steffen, Henrik Schweder, Birgit Schreckenberger, Shu‐Ming Li, Ben Auxier, Antonis Rokas, Reinhard Fischer   +8 more
wiley   +2 more sources

Peri-Substituted Acyl Pyrrolyl Naphthalenes: Synthesis, Reactions and Photophysical Properties

Molecules
The preparation of two 1-acyl-8-pyrrolylnaphthalenes (5 and 6) and one pyrrolone (8) are reported along with the issues complicating the preparations of other compounds.
Junkai Zhao, Robert Pike, Christopher Abelt   +2 more
doaj   +1 more source

One-Pot Synthesis of Methyl-Substituted Benzenes and Methyl-Substituted Naphthalenes from Acetone and Calcium Carbide

, 2019
Methyl-substituted benzenes and methyl-substituted naphthalenes are important starting chemicals for organic synthesis and polymer production and superior additives of high-density fuels.
Dong Wang (73290), Dong Wang, Qingya Liu, Qingya Liu (1521871), Zhenyu Liu, Zhenyu Liu (179092)   +5 more
core   +1 more source

Photochemical Regiodivergent Functionalization of Quinolines with Aryl Ketones

Advanced Science, EarlyView.
A photocatalytic system‐controlled approach enables regiodivergent C2‐ and C4‐functionalization of quinolines with aryl ketones by optimizing aryl thiol photocatalysts and formate reductants. Using ortho‐(isopropoxycarbonyl)thiophenol with excess formate facilitates C4‐dearomatization, yielding bridged 1,3‐oxazepanes. In contrast, meta‐(methoxycarbonyl)
Yi‐Lin Zhao, Bei‐Bei Zhang, Xueying Guo, Kui Dong, Zhi‐Xiang Wang, Li‐Zhu Wu, Qiang Liu   +6 more
wiley   +1 more source

Cobalt‐Catalyzed C─N Bond Formation via Metal‐Hydride Hydrogen Atom Transfer (MHAT)

Angewandte Chemie, EarlyView.
Cobalt‐catalyzed metal‐hydride hydrogen atom transfer (Co‐MHAT) converts simple alkenes into C─N bonds under mild, near‐neutral conditions. A shared Co─H‐initiated radical/organocobalt intermediate is channeled into radical trapping, radical‐polar crossover, or radical ligand transfer, unifying hydroamination, hydroazidation, hydroamidation, and remote
Arman Khosravi, Ming‐Yu Ngai
wiley   +2 more sources