Results 91 to 100 of about 58,835 (270)

Fourth-order derivative spectrophotometric method for simultaneous determination of pseudoephedrine and naproxen in pharmaceutical dosage forms

open access: yesResearch in Pharmaceutical Sciences, 2016
Combination dosage forms of naproxen sodium and pseudoephedrine hydrochloride are used for symptomatic treatment of cold and sinus disorders. In this study, fourth-order derivative spectrophotometric method was used for simultaneous determination of ...
Effat Souri   +2 more
doaj  

Effect of naproxen on oxidative stress biomarkers in Gammarus pulex

open access: yesRevista Científica
Non–steroidal anti–inflammatory drugs (NSAIDs) are a widely prescribed medication class that is used in the treatment of numerous conditions worldwide. Of these drugs, naproxen is the most commonly used NSAID.
Engin Seker
doaj   +1 more source

NAPROXEN INHIBITS THE PROLIFERATION AND MIGRATION OF BREAST CANCER CELLS (MCF-7) THROUGH BCL-2 DOWNREGULATION, CASPASE ACTIVATION, BAX UPREGULATION, AND GENERATION OF EXCESS REACTIVE OXYGEN SPECIES (ROS) [PDF]

open access: yesExploratory Animal and Medical Research
This study explored the antiproliferative activity of naproxen at the molecular level in human breast cancer cell lines, specifically MCF-7. Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely prescribed medications worldwide. Like
Mohammed Al Zharani   +10 more
doaj   +1 more source

Simultaneous separation of naproxen and 6-O-desmethylnaproxen metabolite in saliva samples by liquid chromatography-tandem mass spectrometry: Pharmacokinetic study of naproxen alone and associated with esomeprazole.

open access: yesPLoS ONE, 2020
Naproxen is a widely used non-steroidal anti-inflammatory drug for the control of postoperative inflammatory signs and symptoms in dentistry. Its association with esomeprazole has been widely studied and has yielded good results for the control of acute ...
Thiago José Dionísio   +5 more
doaj   +1 more source

Decreased sensitivity to aspirin is associated with altered polyamine metabolism in human prostate cancer cells [PDF]

open access: yes, 2015
Acknowledgments We thank NHS Grampian for financial support of this work.Peer reviewedPublisher ...
Cameron, Gary A.   +2 more
core   +1 more source

Silent Partners in the Mill: Unveiling the Role of Additives in Mechanochemical Synthesis

open access: yesChemistry – A European Journal, EarlyView.
Mechanochemistry offers a sustainable, solvent‐free alternative to traditional synthesis, often enhanced by additives in a process known as additive‐assisted grinding. This review discusses how various additives, including liquids, ionic solids, and advanced materials like ionic liquids and piezoelectric compounds, improve reaction efficiency ...
Johanna Breinsperger   +3 more
wiley   +1 more source

Removal of emerging pollutants in conventional and microalgae based biotechnology urban wastewater treatment plants [PDF]

open access: yes, 2016
Wastewater treatment plants (WWTPs) reduce portion of the input of pharmaceuticals in aquatic systems, but there is no data available about the elimination of emerging contaminants with microalgae technology.
Baena Nogueras, Rosa María   +5 more
core  

Targeting neuroinflammation in Alzheimer’s disease [PDF]

open access: yes, 2016
Almost 47 million people suffer from dementia worldwide, with an estimated new case diagnosed every 3.2 seconds. Alzheimer’s disease (AD) accounts for approximately 60%–80% of all dementia cases. Given this evidence, it is clear dementia represents one
Bronzuoli, MARIA ROSANNA   +3 more
core   +1 more source

A Streamlined High Performance Liquid Chromatography with Tandem Mass Spectrometry Based Workflow for Rapid Screening of Cellular Accumulation of Small Molecules

open access: yesChemMedChem, EarlyView.
This study uses six small‐molecule inhibitors to evaluate optimal cellular accumulation assay conditions in a 96‐well format with high performance liquid chromatography with tandem mass spectrometry detection. The obtained medium to high‐throughput workflow is suitable for reliably identifying cellular accumulation, valuable for preclinical selection ...
Alina Metzen, Katharina Rox
wiley   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi   +6 more
wiley   +1 more source

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