Results 81 to 90 of about 25,141 (221)
In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates
The present study compares the use of high generation G3 and low generation G0 Polyamidoamine (PAMAM) dendrimers as drug carriers of naproxen (NAP), a poorly water soluble drug.
Mohammad Najlah +4 more
doaj +1 more source
Analgesic effects of platelet‐rich fibrin (PRF): A systematic review
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin +6 more
wiley +1 more source
Formulation and characterization of topical microemulsion loaded with naproxen
The aim of this study was to prepare w/o Micro-emulsions of naproxen for topical application & evaluate in vitro permeation of Naproxen. On the basis of ternary phase diagram and drug solubility test Tween-20, Oleic acid and Polyethylene Glycol 400 ...
Verma, Vivek +2 more
core +1 more source
We present a dual copper/photoredox catalytic system that enables the para‐selective C–H functionalization of benzyl alcohols with sulfenamides. This approach facilitates the para‐selective C–H sulfilimination of benzylic oxime carbonates through an orchestrated sequence involving photoinduced decarboxylation/dearomatization of oxime carbonates, copper‐
Sanhua Zhang +4 more
wiley +1 more source
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique +6 more
wiley +1 more source
Naproxen-induced fixed drug eruption: A case report [PDF]
KARA, ISMAIL HAMDI/0000-0003-2022-1882; KARA, ISMAIL HAMDI/0000-0003-2022-1882WOS: 000296157700016PubMed: 21357631Naproxen is a non-steroidal anti-inflammatory drug (NSAID) widely used for symptomatic relief of arthritis and other painful disorders, such
Davut Baltaci +7 more
core +1 more source
Regulated versus unregulated competition: How drug shortages boost illegal pharmacy sales
Abstract Research Summary This study examines how product shortages among legal firms create competitive opportunities for illegal firms. We analyze 713 drug shortages in the United States between 2017 and 2023 and show that shortages substantially increase illicit pharmacies’ sales of affected drugs, which rise by 40.5% during shortages and remain 32 ...
Luis Diestre, Benjamin Barber IV
wiley +1 more source
Determination of naproxen in human plasma by GC-MS
This paper describes a GC-MS method for the determination of naproxen in human plasma. Naproxen and internal standard ibuprofen were extracted from plasma using a liquid-liquid extraction method.
Sahin, Huseyin +2 more
core +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +1 more source
Bayesian Optimization of Solvent‐Free Thermal Amidation via Reactive Extrusion
Thermal amidation between a carboxylic acid and an amine was successfully conducted in an extruder in the absence of solvent, coupling agent, or catalyst, relying on an adapted Bayesian Optimization protocol. Active pharmaceutical ingredient moclobemide was synthesized on a larger scale, achieving excellent yield and low Process Mass Intensity (PMI ...
Matthieu Lavayssiere +2 more
wiley +1 more source

