Results 61 to 70 of about 25,141 (221)

Submicellar liquid chromatography with fluorescence detection improves the analysis of naproxen in plasma and brain tissue

, 2019
Rapid, simple, and sensitive submicellar liquid chromatography with fluorescence detection was developed and validated to quantify naproxen in plasma and brain samples after oral administration of Naproxen formulations.
Torrado Salmerón, Carlos Félix, Juan José García‐Rodríguez, García Rodríguez, Juan José, Torrado Durán, Guillermo, Guillermo Torrado, Víctor García‐Herrero, García-Rodríguez, Juan José, Torrado, Guillermo, Torrado-Santiago, Santiago, Carlos Torrado‐Salmerón, Santiago Torrado‐Santiago, García-Herrero, Víctor, Torrado Durán, Santiago, Torrado-Salmerón, Carlos   +13 more
core   +1 more source

Simultaneous separation of naproxen and 6-O-desmethylnaproxen metabolite in saliva samples by liquid chromatography-tandem mass spectrometry: Pharmacokinetic study of naproxen alone and associated with esomeprazole.

PLoS ONE, 2020
Naproxen is a widely used non-steroidal anti-inflammatory drug for the control of postoperative inflammatory signs and symptoms in dentistry. Its association with esomeprazole has been widely studied and has yielded good results for the control of acute ...
Thiago José Dionísio, Gabriela Moraes Oliveira, Marina Morettin, Flavio Cardoso Faria, Carlos Ferreira Santos, Adriana Maria Calvo   +5 more
doaj   +1 more source

Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate‐to‐Severe Endometriosis Pain: A Phase III, Multicentric, Double‐Blind, Active‐Controlled, Non‐Inferiority Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate‐to‐severe endometriosis‐associated pain. Design A multicentre, double‐blind, double‐dummy, randomised, parallel‐group, active‐controlled, non‐inferiority phase III study. Setting Nineteen clinical centres across India.
Sneha Bhoir, Jaldhara Patel, Tushar Palve, Mrinal Kanti Dash, Sweety Saigal, Gourisankar Kamilya, Shalini Srivastava, Kartikbhai Savalia, Tanusree Gupta, Deepa Choudhary, Manohar Rangaswamy, Vidya V Bhatt, Neena Gupta, Malathi Ponnuru, Parul Shah, Apurva Shetty, Shruti Saha, Reshma Quadros, Sucheta Pandit, Dipak Patil, Piyush Patel, Pravin Ghadge, Lalit Lakhwani, Suyog Mehta, Sadhana Joglekar   +24 more
wiley   +1 more source

Naproxen-Induced Recurrent Aseptic Meningitis

, 1991
Aseptic meningitis has been linked to treatment with several nonsteroidal antiinflammatory drugs (e.g., ibuprofen, tolmetin, sulindac), particularly in patients with disturbed immunity. Naproxen, however, has only once been reported to cause meningitis.
Babette B. Weksler, Anne Marie Lehany
core   +1 more source

Effect of naproxen on cancellous bone in ovariectomized rats [PDF]

, 2020
Nonsteroidal anti-inflammatory drugs (NSAIDs) affect bone metabolism in vitro and in vivo. They delay but do not alter the outcome of healing processes in bone. In some bone loss models, they block bone resorption and slow the rate of loss.
Coble, Toni, Kimmel, Donald B, Lane, Nancy Dr   +2 more
core   +1 more source

Transition Metal Complexes of Naproxen: Synthesis, Characterization, Forced Degradation Studies, and Analytical Method Verification

Journal of Analytical Methods in Chemistry, 2016
The aim of our current research was to synthesize some transition metal complexes of Naproxen, determine their physical properties, and examine their relative stability under various conditions.
Md. Sharif Hasan, Ruhul Kayesh, Farida Begum, S. M. Abdur Rahman   +3 more
doaj   +1 more source

Artificial Intelligence in Patient Education: ChatGPT for Penile Prosthesis Surgery Counseling, a Likert Scale Analysis

Andrology, EarlyView.
Abstract Introduction Erectile dysfunction (ED) significantly impacts quality of life. For patients unresponsive to conservative treatments, penile prosthesis implantation represents an effective solution with high satisfaction rates. However, the complexity and sensitive nature of the procedure often generate multiple patient concerns.
Gabriele Tulone, Nicola Pavan, Rosa Giaimo, Alchiede Franco Simonato, Alfonzo Salzano, Davide Cosentino, Francesco Claps, Alchiede Simonato   +7 more
wiley   +1 more source

Fourth-order derivative spectrophotometric method for simultaneous determination of pseudoephedrine and naproxen in pharmaceutical dosage forms

Research in Pharmaceutical Sciences, 2016
Combination dosage forms of naproxen sodium and pseudoephedrine hydrochloride are used for symptomatic treatment of cold and sinus disorders. In this study, fourth-order derivative spectrophotometric method was used for simultaneous determination of ...
Effat Souri, Amir Mosafer, Maliheh Barazandeh Tehrani   +2 more
doaj  

NAPROXEN INHIBITS THE PROLIFERATION AND MIGRATION OF BREAST CANCER CELLS (MCF-7) THROUGH BCL-2 DOWNREGULATION, CASPASE ACTIVATION, BAX UPREGULATION, AND GENERATION OF EXCESS REACTIVE OXYGEN SPECIES (ROS) [PDF]

Exploratory Animal and Medical Research
This study explored the antiproliferative activity of naproxen at the molecular level in human breast cancer cell lines, specifically MCF-7. Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely prescribed medications worldwide. Like
Mohammed Al Zharani, Eman Almuqri, Mohammed Mubarak, Nada Aljarba, Hassan Rudayni, Shaikha A. Albatli, Khadijah Yaseen, Saad Alkahtani, Fahd A. Nasr, Amin A. Al Doaiss, Mohammed S. Al eissa   +10 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source