Results 81 to 90 of about 58,835 (270)

Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles [PDF]

, 2012
The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels.
Mucalo, Michael R., Rathbone, Michael J.
core   +1 more source

The Impact of Nonsteroidal Anti‐Inflammatory Drugs on Radiographic Spinal Progression in Patients With Axial Spondyloarthritis: 10‐Year Results From an Inception Cohort

Arthritis &Rheumatology, EarlyView.
Objective This study aims to investigate the impact of nonsteroidal anti‐inflammatory drug (NSAID) intake on radiographic spinal progression in axial spondyloarthritis (axSpA), considering different NSAID types (COX‐2 inhibitors [COX2i] and nonselective NSAIDs [ns‐NSAIDs]) and disease subgroups (radiographic [r‐axSpA] and nonradiographic [nr‐axSpA ...
Murat Torgutalp, Valeria Rios Rodriguez, Fabian Proft, Mikhail Protopopov, Judith Rademacher, Hildrun Haibel, Joachim Sieper, Martin Rudwaleit, Denis Poddubnyy   +8 more
wiley   +1 more source

Correlations between electrochemical behaviors and DNA photooxidative properties of non-steroïdal anti-inflammatory drugs and their photoproducts [PDF]

, 2012
Alkali-labile lesion to DNA photosensitized, via an electron transfer mechanism, by three non-steroidalanti-inflammatorydrugs (NSAIDs), ketoprofen, tiaprofenic acid and naproxen and their photoproducts during drug photolysis, was investigated using 32P ...
Chouini-Lalanne, Nadia, Fabre, Paul-Louis, Hajj, Viviane, Latapie, Laure, Michaud, Sandra, Noirot, Arielle, Sartor, Valérie   +6 more
core   +2 more sources

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

Transition Metal Complexes of Naproxen: Synthesis, Characterization, Forced Degradation Studies, and Analytical Method Verification

Journal of Analytical Methods in Chemistry, 2016
The aim of our current research was to synthesize some transition metal complexes of Naproxen, determine their physical properties, and examine their relative stability under various conditions.
Md. Sharif Hasan, Ruhul Kayesh, Farida Begum, S. M. Abdur Rahman   +3 more
doaj   +1 more source

Thrombosis Is Reduced by Inhibition of COX-1, but Unaffected by Inhibition of COX-2, in an Acute Model of Platelet Activation in the Mouse [PDF]

, 2011
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
BB Dawood, BF McAdam, BJ Whittle, C Baigent, C Bombardier, C Moore, C Patrono, C Patrono, C Patrono, C Tymvios, CM Potter, D Pratico, EM Antman, F Catella-Lawson, F Giuliano, F Giuliano, G Davi, Harald H. H. W. Schmidt, JA Mitchell, Jane A. Mitchell, JJ Talley, LK Jennings, Michael Emerson, MJ Cho, N Zidar, NA Flavahan, Nicholas S. Kirkby, Paul C. Armstrong, PC Armstrong, PM Kearney, RF Storey, RJ Gryglewski, S Cronberg, S Krishnamurthi, S Moncada, SP Jackson, T Grosser, TD Warner, TD Warner, TD Warner, Timothy D. Warner, TT Niemi, WB White, Zetty N. Zain   +43 more
core   +4 more sources

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Use of an Evidence‐Based Guideline for Management of Side Effects from Long‐Acting Reversible Contraceptives: A Quality Improvement Report [PDF]

, 2018
Introduction Many health care providers believe that women who initiate long‐acting reversible contraceptives (LARC) discontinue the method because of side effects too soon for the method to be economical.
Glantz, J. Christopher, Jacobson, Julia, Nasso, Jacqueline   +2 more
core   +1 more source

Open-label randomised pragmatic trial (CONTACT) comparing naproxen and low-dose colchicine for the treatment of gout flares in primary care

Annals of the Rheumatic Diseases, 2019
Objectives To compare the effectiveness and safety of naproxen and low-dose colchicine for treating gout flares in primary care. Methods This was a multicentre open-label randomised trial.
E. Roddy, K. Clarkson, M. Blagojevic-Bucknall, R. Mehta, Raymond Oppong, A. Avery, E. Hay, C. Heneghan, L. Hartshorne, J. Hooper, Gemma Hughes, S. Jowett, Martyn Lewis, P. Little, K. McCartney, K. Mahtani, D. Nunan, M. Santer, Sam Williams, C. Mallen   +19 more
semanticscholar   +1 more source

Digitally guided corticotomy using a customized surgical template (Suya corticotomy utility template): A technique report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Precise control of corticotomy lines is critical in surgically facilitated orthodontic therapy. The Suya method is traditionally performed freehand, which introduces risks of root damage and procedural inconsistency. A digitally guided protocol may address these limitations by enhancing safety and technical predictability. Methods A
Yosuke Tsukiboshi, Jaewon Choi, Takuma Fukumoto, Ryo Nakajima   +3 more
wiley   +1 more source