Results 151 to 160 of about 43,002 (287)
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation.
Cell, 1999 R. Chemelli +14 more
semanticscholar +1 more source
Age at Onset and Delays in Diagnosis of Central Disorders of Hypersomnolence Over the Past 30 Years
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Patients with narcolepsy type 1 (NT1), type 2 (NT2), idiopathic hypersomnia (IH) usually suffer from symptoms for years, even decades, before being diagnosed. We aimed to assess age at onset, age at diagnosis and changes in the diagnostic delays of these patients from 1990 to 2020 in a single centre.
Zhongxing Zhang +4 more
wiley +1 more source
Sleep and Rhythmic Profile After Pineal Gland Removal in Humans
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Melatonin, a hormone produced by the pineal gland, is classically described as a central circadian modulator. However, the impact of its absence on circadian rhythmicity in humans remains poorly understood. Pinealectomised patients, in whom melatonin secretion is chronically suppressed, represent a valuable clinical model to investigate the ...
Renata de Andrade Prado Gobetti +7 more
wiley +1 more source
Development of the pediatric narcolepsy patient-reported outcomes scale (PN-PROs)
Frontiers in SleepBackgroundPediatric narcolepsy is a chronic neurological disorder that impacts the health and overall wellbeing of children and adolescents with the disease.
Grace Y. Wang +10 more
doaj +1 more source
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Data from the REST‐ON trial were not available before the 2021 American Academy of Sleep Medicine (AASM) clinical practice guideline update, which included a literature review through August 2020. This post hoc analysis from REST‐ON assessed participants who achieved clinically significant improvements on individual AASM clinical significance ...
Luis E. Ortiz +7 more
wiley +1 more source
Treatment of narcolepsy and pregnancy: a review
Sleep Science and PracticeThis is a chapter review of pregnancy state in patients with narcolepsy which aims to provide a review of literature regarding pregnancy in patients with narcolepsy, physiology of hormonal change during pregnancy on sleep, pharmacologic and non ...
Kullatham Kongpakpaisarn, Christine Won
doaj +1 more source
Sleep-wake cycle effects on sleep stages, and plasma cortisol and growth secretions [PDF]
Studies were made of the effects of various stimuli on sleep stages and of secretion of a number of different hormones during sleep in human subjects. Among the stimuli were vestibular stimulation, the action of L-Dopa, and a three-hour sleep-wake cycle.
core +1 more source
Facial Emotion Recognition in Children With Narcolepsy Type 1
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Narcolepsy type 1 is a neurological disorder typically emerging in childhood or adolescence, characterised by excessive daytime sleepiness, cataplexy and rapid eye movement sleep‐related symptoms. Beyond its core features, increasing evidence suggests an impact on socio‐cognitive development, including difficulties in understanding others ...
Marco Veneruso +11 more
wiley +1 more source
Journal of Sleep Research, Volume 35, Issue 2, April 2026.ABSTRACT Irregular sleep is increasingly related to poorer health, with stronger links to cardiovascular disease and mortality than sleep duration. Its impact on health‐related quality of life, however, remains unclear, particularly in community‐based populations.
Kelly Sansom +8 more
wiley +1 more source
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae +53 more
wiley +1 more source