Results 171 to 180 of about 15,506 (210)
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The Lancet, 2007
Narcolepsy with cataplexy is a disabling sleep disorder affecting 0.02% of adults worldwide. It is characterised by severe, irresistible daytime sleepiness and sudden loss of muscle tone (cataplexy), and can be associated with sleep-onset or sleep-offset paralysis and hallucinations, frequent movement and awakening during sleep, and weight gain.
Yves, Dauvilliers +2 more
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Narcolepsy with cataplexy is a disabling sleep disorder affecting 0.02% of adults worldwide. It is characterised by severe, irresistible daytime sleepiness and sudden loss of muscle tone (cataplexy), and can be associated with sleep-onset or sleep-offset paralysis and hallucinations, frequent movement and awakening during sleep, and weight gain.
Yves, Dauvilliers +2 more
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Seminars in Pediatric Neurology, 2001
Core symptoms of narcolepsy are similar in children compared with adults, but expression may be different due to more severe manifestations, maturational factors, and the significant impact of symptoms on behavior and academic performance. Diagnosis of narcolepsy in children is often challenging and requires a detailed history followed by ...
M S, Wise, J, Lynch
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Core symptoms of narcolepsy are similar in children compared with adults, but expression may be different due to more severe manifestations, maturational factors, and the significant impact of symptoms on behavior and academic performance. Diagnosis of narcolepsy in children is often challenging and requires a detailed history followed by ...
M S, Wise, J, Lynch
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Annual Review of Genomics and Human Genetics, 2003
▪ Abstract Human narcolepsy is a genetically complex disorder. Family studies indicate a 20–40 times increased risk of narcolepsy in first-degree relatives and twin studies suggest that nongenetic factors also play a role. The tight association between narcolepsy-cataplexy and the HLA allele DQB1*0602 suggests that narcolepsy has an autoimmune ...
Dorothee, Chabas +3 more
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▪ Abstract Human narcolepsy is a genetically complex disorder. Family studies indicate a 20–40 times increased risk of narcolepsy in first-degree relatives and twin studies suggest that nongenetic factors also play a role. The tight association between narcolepsy-cataplexy and the HLA allele DQB1*0602 suggests that narcolepsy has an autoimmune ...
Dorothee, Chabas +3 more
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Sleep Medicine Reviews, 2009
Narcolepsy is a chronic disease commonly diagnosed in middle adulthood. However, the first symptoms often appear in childhood and/or adolescence. Pediatric cases of narcolepsy are among the most often underrecognised and underdiagnosed diseases. This fact raises questions about the reasons for such diagnostic delay from the clinical point of view, and ...
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Narcolepsy is a chronic disease commonly diagnosed in middle adulthood. However, the first symptoms often appear in childhood and/or adolescence. Pediatric cases of narcolepsy are among the most often underrecognised and underdiagnosed diseases. This fact raises questions about the reasons for such diagnostic delay from the clinical point of view, and ...
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Archives of Neurology, 1980
To the Editor.— I read with interest the article in theArchivesby Kales et al (36:650-651, 1979) regarding treatment of narcolepsy with propranolol, particularly in view of demonstrated hyperresponsiveness to β-adrenergic stimulation in patients with primary disorders of impaired wakefulness.
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To the Editor.— I read with interest the article in theArchivesby Kales et al (36:650-651, 1979) regarding treatment of narcolepsy with propranolol, particularly in view of demonstrated hyperresponsiveness to β-adrenergic stimulation in patients with primary disorders of impaired wakefulness.
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2011
Abstract The term “narcolepsy” was first coined by Gelineau in 1880 with the complete description of a patient with excessive daytime sleepiness (EDS), sleep attacks, and episodes of muscle weakness triggered by emotions. In the current international classification, narcolepsy is characterized by “excessive daytime sleepiness that is typically ...
Seiji, Nishino, Emmanuel, Mignot
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Abstract The term “narcolepsy” was first coined by Gelineau in 1880 with the complete description of a patient with excessive daytime sleepiness (EDS), sleep attacks, and episodes of muscle weakness triggered by emotions. In the current international classification, narcolepsy is characterized by “excessive daytime sleepiness that is typically ...
Seiji, Nishino, Emmanuel, Mignot
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Veterinary Clinics of North America: Small Animal Practice, 1980
A S, Foutz, M M, Mitler, W C, Dement
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A S, Foutz, M M, Mitler, W C, Dement
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Seminars in Pediatric Neurology, 1996
Childhood narcolepsy is frequently under-diagnosed. Hypersomnolence may not always be accompanied by cataplexy, sleep paralysis, or hypnagogic hallucinations in the early stages. Pathophysiologic considerations revolve around an altered central nervous system catecholamine-acetylcholine balance. Both idiopathic and symptomatic forms have been described.
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Childhood narcolepsy is frequently under-diagnosed. Hypersomnolence may not always be accompanied by cataplexy, sleep paralysis, or hypnagogic hallucinations in the early stages. Pathophysiologic considerations revolve around an altered central nervous system catecholamine-acetylcholine balance. Both idiopathic and symptomatic forms have been described.
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Neurology, 1998
Narcolepsy may present during childhood and is probably underrecognized and underdiagnosed in this population. The core symptoms of narcolepsy in children are similar to those in adults, but the expression may be different because of maturational factors.
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Narcolepsy may present during childhood and is probably underrecognized and underdiagnosed in this population. The core symptoms of narcolepsy in children are similar to those in adults, but the expression may be different because of maturational factors.
openaire +2 more sources