Results 1 to 10 of about 13,161 (220)

Increased Numbers of CD4⁺ T-Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1. [PDF]

Ann Neurol
Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Shan L, Fonville M, Hoekstra M, Fronczek R, Smolders J, Swaab DF.   +5 more
europepmc   +2 more sources

Editorial: Hypocretins/Orexins

Frontiers in Endocrinology, 2020
Miguel López, Miguel López, Luis de Lecea, Carlos Diéguez, Carlos Diéguez   +4 more
doaj   +3 more sources

Editorial: Neuromodulation of mood and eating behavior. [PDF]

Front Neurosci
de Gortari P, Alcántara-Alonso V, García-Luna C.   +2 more
europepmc   +1 more source

Narcolepsy: Pathophysiology, Diagnosis, Management, and Future Directions, a Narrative Review. [PDF]

Brain Behav
Hastings NE, Abdi KE, Bibi F, Aslam B, Nuñez MR, Sherani MTR, Shadmani S, Alam U, Hassan VM, Hoor-E-Ainaa, Imran H, Hanna J, Sadat SH.   +12 more
europepmc   +1 more source

Beyond conventional polysomnography: advanced sleep feature engineering and machine learning for differentiating central disorders of hypersomnolence. [PDF]

Sleep
Zhang Z, Khatami R.
europepmc   +1 more source

Beyond neuronal loss: epigenetic signatures bridging immune activation and sleep dysfunction in narcolepsy type 1. [PDF]

Sleep
BaHammam AS.
europepmc   +1 more source

Animal Models of Narcolepsy: From Orexin Deficiency to Immune Mechanisms and Regenerative Therapies. [PDF]

Curr Issues Mol Biol
Arias-Carrión O, Ortega-Robles E.
europepmc   +1 more source

Significance of neuroendocrine systems and the gut-brain axis (GBA) in the regulation of obesity. [PDF]

PeerJ
Zhao H, Li Y, Cheng R, Wang Y, Ma L, Chen W.   +5 more
europepmc   +1 more source

Indole Loss: Hypertensive Link Between Dysbiosis and Diastolic Heart Failure. [PDF]

Circ Res
Horner KB, Mutchler AL.
europepmc   +1 more source

Narcolepsy Associated With Streptococcal Infection: A Case Report and Literature Review. [PDF]

Clin Case Rep
Zhu Z, Zhang Q, Hu S, Yan C, Jiang W, Ji Y.   +5 more
europepmc   +1 more source