Results 161 to 170 of about 43,002 (287)
Validation of the Russian version of Swiss Narcolepsy Scale for narcolepsy type 1 screening
Ullanlinna Narcolepsy Scale (UNS) is the most widely used scale for primary screening for narcolepsy. It has a high sensitivity (83.5 %) and specificity (84.1 %).
A. O. Golovatyuk +5 more
doaj +1 more source
Wake‐promoting neuromodulators in Alzheimer's disease: Implications for sleep and brain clearance
Abstract Neuromodulatory subcortical systems (NSS) regulate arousal, cognition, and sleep–wake transitions through widespread influence on cortical and subcortical networks. Increasing evidence links dysfunction of these systems to the pathogenesis of Alzheimer's disease (AD). Degeneration and dysregulation of NSS occurs during the preclinical phase of
Taylor J. Pedersen +7 more
wiley +1 more source
No persistent effect of intravenous immunoglobulins in patients with narcolepsy with cataplexy [PDF]
We report on four patients with narcolepsy with cataplexy (NC), who were treated with high-dose intravenous immunoglobulins (IVIg). Although in some patients transient effects were seen of both objective (multiple sleep latency test and maintenance of ...
Bassetti, C. +3 more
core
Sleep disorders and sleep behaviors as predictors of neurodegenerative diseases
Abstract INTRODUCTION The impact of sleep disorders (SDs) on incident neurodegenerative disease (NDD) risk has not been comprehensively investigated. METHODS In the UK Biobank cohort, 30,032 participants with SDs (defined by diagnostic codes) and 147,321 without SDs were included.
Taewon Kim +7 more
wiley +1 more source
Abnormal activity in hypothalamus and amygdala during humour processing in human narcolepsy with cataplexy [PDF]
Narcolepsy with cataplexy (NC) is a complex sleep-wake disorder, which was recently found to be associated with a reduction or loss of hypocretin (HCRT, also called orexin). HCRT is a hypothalamic peptide implicated in the regulation of sleep/wake, motor
Bassetti, C L. +6 more
core
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard +2 more
wiley +1 more source
A 12‐year‐old girl with Klein‐Levin syndrome showed central hypopneas and REM sleep without atonia on 24‐h polysomnography, which normalized after clarithromycin treatment alongside clinical remission. ABSTRACT Kleine–Levin syndrome (KLS) is a rare disorder with limited literature on treatment options and efficacy, especially in adolescents.
Sarisa Thawongit +2 more
wiley +1 more source
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden +6 more
wiley +1 more source

