Results 181 to 190 of about 7,248 (208)
Some of the next articles are maybe not open access.
STRUCTURAL FEATURES ASSOCIATED WITH NARCOTICS AND NARCOTIC ANTAGONISTS
Neuropharmacology, 1975Viminol shares many pharmacological properties of the traditional narcotics, but it differs from the latter because it has an extremely reduced capacity for producing physical dependence. This chapter discusses the types of pharmacological activity related to the structural features of the Viminol stereoisomers.
openaire +3 more sources
Clinical Principles for the Narcotic Antagonists
Postgraduate Medicine, 1957(1957). Clinical Principles for the Narcotic Antagonists. Postgraduate Medicine: Vol. 22, No. 6, pp. 566-571.
Max S. Sadove, M. J. Schiffrin
openaire +3 more sources
Narcotic Antagonists: A Reasonable Method of Treating Narcotic Dependency
International Journal of the Addictions, 1975Historically, narcotic dependence has been treated primarily by substituting one narcotic drug for another. One alternative chemical treatment for narcotic dependency is through the use of a narcotic antagonist. The present study involves the observed side effects and outcome results of treating 40 male heroin addicts with the narcotic antagonist ...
Kenneth G. Schooff +2 more
openaire +3 more sources
Discriminative Properties of Narcotic Antagonists
1977There have been many recent reports characterizing the discriminative properties of morphine and related narcotic analgesics in a variety of experimental paradigms, predominantly in the rat (see preceding chapter). It is becoming increasingly evident that a strong association exists between the discriminative properties of these drugs in animals and ...
Stephen G. Holtzman +2 more
openaire +3 more sources
On the ability of narcotic antagonists to produce the narcotic cue.
The Journal of Pharmacology and Experimental Therapeutics, 1976The ability of narcotic antagonists to produce the narcotic cue was investigated in rats trained to discriminate fentanyl (0.04 mg/kg) from solvent. The partial antagonists pentazocine, cyclazocine and nalorphine were found to possess narcotic cuing activity whereas naloxone lacked any such action at doses up to 160 mg/kg.
F C, Colpaert +2 more
openaire +2 more sources
Journal of Medicinal Chemistry, 1975
A series of new narcotic antagonists has been synthesized by modifying the C-6 carbonyl group in naloxone (Ia) and naltrexone (Ib). New functional units were introduced by reaction with various phosphorus and sulfur ylides and alkyllithium reagents.
Hahn Ef, Fishman J, Heilman Rd
openaire +3 more sources
A series of new narcotic antagonists has been synthesized by modifying the C-6 carbonyl group in naloxone (Ia) and naltrexone (Ib). New functional units were introduced by reaction with various phosphorus and sulfur ylides and alkyllithium reagents.
Hahn Ef, Fishman J, Heilman Rd
openaire +3 more sources
Community Outcome on Narcotic Antagonists [PDF]
, 1979 As described at the outset of this book, there were two general goals of this research program: (1) a multivariate assessment of blocked and unblocked heroin consumption in order to characterize the nature of opioid reinforcement and (2) an approach to developing and evaluating narcotic antagonist treatment for the individual addict.
Steven M. Mirin +2 more
openaire +1 more source
Aftercare on Narcotic Antagonists: Prospects and Problems
International Journal of the Addictions, 1976This study examines the problems and prospects of aftercare of the multiple treatment failure opiate addict who is being treated with narcotic antagonists (primarily naltrexone). At the time of this paper, 21 patients had been admitted to the Drug Addiction Research Project at McLean Hospital, with a retention rate of 42%. "Completers," "noncompleters,"
Maxine Rawlins +4 more
openaire +3 more sources
Narcotic and Narcotic Antagonist Analgesics
Annual Review of Pharmacology, 1967L S Harris, H F Fraser
openaire +3 more sources
Recent Progress in Research on Narcotic Antagonists
1976In Volume 8 of this series Archer and Harris [7] reviewed the chemistry and pharmacology of narcotic antagonists. Since that time research in this field has increased enormously as evidenced by the fact that in the decade 1962–72 over 500 references to pentazocine have appeared in the literature.
William F. Michne, Sydney Archer
openaire +3 more sources