Results 61 to 70 of about 13,397 (249)
Abstract Background Pain management is a critical part of treatment in patients with chest trauma. Opioids and nonsteroidal anti‐inflammatory drugs have been the most commonly used medications. However, their side effects have drawn attention to other medications.
Hossein Zabihi Mahmoodabadi+4 more
wiley +1 more source
Method of Administering Narcotic Antagonists and Analgesics and Novel Dosage Forms Containing Same [PDF]
The invention provides a novel method of administering narcotic antagonists, narcotic analgesics and related compounds, and novel dosage forms containing those compounds which are adapted for nasal administration. The nasal dosage forms disclosed include
Hussain, Anwar A.
core +1 more source
Border fortification and legibility: Evidence from Afghanistan
Abstract States often fortify their borders against militant threats. How do these efforts shape civilian welfare and perceptions in borderland communities? I conceptualize border fortification as a legibility‐building endeavor. By bolstering state reach in areas of weak historical penetration, fortification enhances the government's capacity for ...
Christopher W. Blair
wiley +1 more source
Antidepressant-like Effects of Neuropeptide SF (NPSF) [PDF]
Neuropeptide SF (NPSF) is a member of RFamide neuropeptides that play diverse roles in central nervous system. Little is know about the effects of NPSF on brain functions. Antidepressant-like effect of NPSF was studied in modified mice FST. NPSF showed the antidepressant-like effects by decreasing the immobility time and increasing the climbing and ...
arxiv
dissertationRecent investigations clarifying the monoaminergic influences on sympathetic preganglionic neurons in the cat have allowed a direct assessment of the effects of narcotic analgesics and antagonists on central transmission.
McCloskey, Kevin Lee.
core
Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra+4 more
wiley +1 more source
Spontaneous and pharmacologically induced hypothermia protect mice against endotoxic shock
Background and Purpose Despite the well‐known occurrence of hypothermia during sepsis, its underlying biological nature and adaptive value remain debated. Experimental Approach Using indirect calorimetry, telemetry, thermal gradient studies and pharmacological studies, we examined the thermal and metabolic responses of mice treated with a shock ...
Arely Tinajero+7 more
wiley +1 more source
Altruism and Antagonistic Pleiotropy in Penna Ageing Model [PDF]
The Penna ageing model is based on mutation accumulation theory. We show that it also allows for self-organization of antagonistic pleiotropy which helps at young age at the expense of old age. This can be interpreted as emergence of altruism.
arxiv
Changes in the Cell Squad of Iliac Lymph Nodes of White Rats in Case of Longterm Influence of Nalbufin [PDF]
The article presents data on the change in the cellular composition of the lymph nodes of the white rats, males of reproductive age, who received intramuscular opioid analgesics - nalbuphine every day for six weeks.
Holovatskyi, A. (Andrew)+1 more
core
Abstract In their 2022 study, ‘The Effects of Naloxone Access Laws on Opioid Abuse, Mortality, and Crime,’ Doleac and Mukherjee conclude that broadening access to a life‐saving drug—naloxone—does not reduce opioid‐related mortality as the drug simultaneously encourages riskier drug use. I show issues with their data, design, and estimation methods. For
Sergey Alexeev
wiley +1 more source