The clinical application progress of multimodal analgesia strategy in enhanced recovery after surgery: a narrative review. [PDF]
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Willingness to provide naloxone: Survey of the National Dental Practice-Based Research Network. [PDF]
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The role of central versus peripheral opioid receptors in fentanyl-induced brain hypoxia. [PDF]
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Optimizing Antiemetic Strategies Across Phases of Chemotherapy-Induced Nausea and Vomiting: Real-World Evidence in Breast Cancer. [PDF]
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Narcotic Antagonists as Analgesics
Science, 19622-Dimethylallyl-5,9-dimethyl-2′-hydroxybenzomorphan (Win 20,228) was found to be a weak antagonist of morphine and meperidine, whereas 2-allyl-5-ethyl-2′-hydroxy-9-methyl-6,7-benzomorphan (Win 19,362) and 2-allyl-2′-hydroxy-5,9-dimethyl-6,7-benzomorphan (Win 19,631) were about three times as potent as nalorphine.
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CLINICAL PHARMACOLOGY OF NARCOTIC ANTAGONISTS*
Annals of the New York Academy of Sciences, 1978Both naloxone and naltrexone are effective narcotic antagonists with minimal agonistic effects and a wide margin of safety. Naloxone is useful in the treatment of narcotic overdose and it is helpful in the quantification of physical dependence. Naltrexone is pharmacologically successful as an orally effective, long-acting antagonist but its clinical ...
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COMPARATIVE STUDIES WITH NARCOTICS AND NARCOTIC ANTAGONISTS IN MAN
Acta Anaesthesiologica Scandinavica, 1964ZUSAMMENFASSUNGBei 240 oberflächlich anaesthesierten Patienten, die keine Narkotika als Prämedikation erhalten hatten, wurden die Wirkungen auf Atmung und Kreislauf der folgenden Mittel, allein oder in verschiedenen Kombinationen verabreicht, untersucht: Morphin (0,2 oder 0,3 mg/kg), Oxymorphon(20 μ/kg),Levorphan (50μ/kg),Meperidin (1,5 und 2,0 mg/kg ...
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