Results 141 to 150 of about 12,456 (182)

Narcotic antagonists. 4. Carbon-6 derivatives of N-substituted noroxymorphones as narcotic antagonists

Journal of Medicinal Chemistry, 1975
A series of new narcotic antagonists has been synthesized by modifying the C-6 carbonyl group in naloxone (Ia) and naltrexone (Ib). New functional units were introduced by reaction with various phosphorus and sulfur ylides and alkyllithium reagents.
R D, Heilman, E F, Hahn, J, Fishman
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EVALUATION OF NARCOTIC AND NARCOTIC ANTAGONIST INTERACTIONS IN PRIMATES*

Annals of the New York Academy of Sciences, 1976
Multiple and single drug interactions were studied in morphine-dependent monkeys whose dependency was maintained by self-infusion. Naloxone, naltrexone, and cyclazocine precipitated abstinence syndrome which the animals generally controlled with increased morphine intake.
K F, Killam, M J, Brocco, C A, Robinson
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Narcotic Antagonists: A Reasonable Method of Treating Narcotic Dependency

International Journal of the Addictions, 1975
Historically, narcotic dependence has been treated primarily by substituting one narcotic drug for another. One alternative chemical treatment for narcotic dependency is through the use of a narcotic antagonist. The present study involves the observed side effects and outcome results of treating 40 male heroin addicts with the narcotic antagonist ...
K G, Schooff, R G, Hersch, J F, Keegan
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STRUCTURAL FEATURES ASSOCIATED WITH NARCOTICS AND NARCOTIC ANTAGONISTS

Neuropharmacology, 1975
Viminol shares many pharmacological properties of the traditional narcotics, but it differs from the latter because it has an extremely reduced capacity for producing physical dependence. This chapter discusses the types of pharmacological activity related to the structural features of the Viminol stereoisomers.
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Discriminative Properties of Narcotic Antagonists

1977
There have been many recent reports characterizing the discriminative properties of morphine and related narcotic analgesics in a variety of experimental paradigms, predominantly in the rat (see preceding chapter). It is becoming increasingly evident that a strong association exists between the discriminative properties of these drugs in animals and ...
S G, Holtzman, H E, Shannon, G J, Schaefer   +2 more
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Clinical Principles for the Narcotic Antagonists

Postgraduate Medicine, 1957
(1957). Clinical Principles for the Narcotic Antagonists. Postgraduate Medicine: Vol. 22, No. 6, pp. 566-571.
M S, SADOVE, M J, SCHIFFRIN
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NARCOTIC–NARCOTIC ANTAGONIST MIXTURES

Anesthesiology, 1961
J, TELFORD, A S, KEATS
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Narcotic and Narcotic Antagonist Analgesics

Annual Review of Pharmacology, 1967
H F, Fraser, L S, Harris
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Narcotics and Narcotic Antagonists

Anesthesiology, 1965
FRANCIS F. FOLDES, MARK SWERDLOW, EPHRAIM S. SIKER   +2 more
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Narcotic Antagonists

1965
S, Archer, L S, Harris
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