Patterns in meperidine distribution and associations with income and obesity in the USA and Puerto Rico between 2019 and 2023: a retrospective study [PDF]
Objectives Meperidine, once viewed as relatively safe, is now discouraged in clinical settings due to its associated risks. Previous studies have identified a significant decrease in meperidine distribution across the USA from 2000 to 2021.
Brian J Piper +3 more
doaj +2 more sources
Comparative Analysis of Preoperative Sedation Modalities: Oral Midazolam and Ketamine Versus Chloral Hydrate and Meperidine in Pediatric Tonsillectomy - A Randomized Clinical Trial [PDF]
Objective: A pre-anesthetic medication that is ideal for pediatric patients undergoing tonsillectomy should alleviate pediatric anxiety, facilitate the smooth induction of anesthesia, and have an analgesic effect for postoperative care.
Nima Naderi +5 more
doaj +2 more sources
Investigation of the effects of systemic meperidine administration on fascia healing in an experimental rat model [PDF]
Purpose: To evaluate the effects of meperidine on fascial healing. Methods: Seventy adult male Sprague-Dawley rats divided into 7 groups with 10 rats in each group.
Emine Sensoy +6 more
doaj +2 more sources
Comparison of Fentanyl versus Meperidine in Combination with Midazolam for Sedative Colonoscopy in Korea [PDF]
Background/Aims Combination of midazolam and opioids is used widely for endoscopic sedation. Compared with meperidine, fentanyl is reportedly associated with rapid recovery, turnover rate of endoscopy room, and quality of endoscopy.
Gwan Woo Hong +12 more
doaj +1 more source
Declines and pronounced regional disparities in meperidine use in the United States
There have been increasing concerns about adverse effects and drug interactions with meperidine. The goal of this study was to characterize meperidine use in the United States.
John M. Boyle +3 more
doaj +1 more source
Epidural analgesia (EA) is one of the best pain relief for many pregnant women in labor. This study was conducted to evaluate the effect of epidural analgesia provided by a combination of bupivacaine plus meperidine or fentanyl on the mother, fetus, and
Masoomeh Nataj Majd +4 more
doaj +1 more source
Post anesthesia shivering (PAS) is a repetitive involuntary movement of one or more muscle groups as a result of a decrease in core body temperature. Pharmacological therapy in preventing PAS may include meperidine and paracetamol.
Mario Nataputra +2 more
doaj +1 more source
Effect of Meperidine on Equine Blood Histamine, Tryptase, and Immunoglobulin-E Concentrations
Objectives: To evaluate changes in immunological parameters following subcutaneous (SC) and intramuscular (IM) administration of meperidine in horses through quantitative analysis of plasma tryptase, histamine, and IgE levels.Methods: Six adult horses ...
H. Nicole Trenholme +11 more
doaj +1 more source
Background and Objectives: The purpose of the study was to investigate the role of adrenaline (ADR), noradrenaline (NDR), and cortisol in the pathogenesis of the analgesic potency, duration, and epilepsy-like toxic effect of meperidine.
Mehmet Yilmaz +5 more
doaj +1 more source
Pronounced Declines in Meperidine in the US: Is the End Imminent?
Background: Once a widely used analgesic in the United States (US), meperidine offered an alternative opioid to other opioids as a pain reliever and was widely assumed to be safer with acute pancreatitis.
Lavinia R. Harrison +8 more
doaj +1 more source

