Results 111 to 120 of about 672,472 (195)

Narcotic Antagonists

Science, 1972
exaly   +3 more sources

The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests.

Journal of Pharmacology and Experimental Therapeutics, 1970
We have investigated the effect of a number of agents which alter central neurohumeral tone on the activity of morphine and the narcotic antagonists in the tail-flick and the phenylquinone tests.
W. Dewey, L. Harris, J. Howes, J. A. Nuite   +3 more
semanticscholar   +1 more source

Quantification of the analgesic activity of narcotic antagonists by a modified hot-plate procedure.

Journal of Pharmacology and Experimental Therapeutics, 1975
The analgesic activity of morphine and the narcotic antagonists, pentazocine, cyclazocine, levallorphan and nalorphine, was assessed in the rat using two hot plates: one maintained at 49.5 degrees C and the other at the "standard" 54.5 degrees C.
J. O'Callaghan, S. Holtzman
semanticscholar   +1 more source

Narcotic Antagonists as Analgesics

Science, 1962
2-Dimethylallyl-5,9-dimethyl-2′-hydroxybenzomorphan (Win 20,228) was found to be a weak antagonist of morphine and meperidine, whereas 2-allyl-5-ethyl-2′-hydroxy-9-methyl-6,7-benzomorphan (Win 19,362) and 2-allyl-2′-hydroxy-5,9-dimethyl-6,7-benzomorphan (Win 19,631) were about three times as potent as nalorphine.
S, ARCHER, N F, ALBERTSON, L S, HARRIS, A K, PIERSON, J G, BIRD, A S, KEATS, J, TELFORD, C N, PAPADOPOULOS   +7 more
openaire   +2 more sources

Research on Narcotic Antagonists

Science, 1971
exaly   +3 more sources

Antagonism of the behavioral effects of morphine and methadone by narcotic antagonists in the pigeon.

Journal of Pharmacology and Experimental Therapeutics, 1970
The effects of narcotics and narcotic antagonists, alone and in combination, were studied on the schedule-controlled behavior of the pigeon. Morphine and methadone increased the rate of responding under the fixed-interval component of a multiple fixed ...
D. McMillan, P. Wolf, R. Carchman
semanticscholar   +1 more source

NARCOTIC ANTAGONISTS

Anesthesiology, 1961
L. Goldstein, J. Aldunate
exaly   +2 more sources

On the ability of narcotic antagonists to produce the narcotic cue.

Journal of Pharmacology and Experimental Therapeutics, 1976
The ability of narcotic antagonists to produce the narcotic cue was investigated in rats trained to discriminate fentanyl (0.04 mg/kg) from solvent. The partial antagonists pentazocine, cyclazocine and nalorphine were found to possess narcotic cuing ...
F. Colpaert, C. Niemegeers, P. Janssen
semanticscholar   +1 more source

ACIDOSIS LOWERS IN-VIVO POTENCY OF NARCOTICS AND NARCOTIC ANTAGONISTS AND CAN EVEN ABOLISH NARCOTIC ANTAGONIST ACTIVITY

Lancet, The, 1982
Joseph J Kaufman
exaly   +3 more sources

Use of narcotic antagonists to modify stereotypic self-licking, self-chewing, and scratching behavior in dogs.

Journal of the American Veterinary Medical Association, 1988
We evaluated 2 narcotic antagonists, naltrexone and nalmefene, for treatment of refractory self-licking, self-chewing, and scratching behavior in dogs. Eleven dogs with various irritative or pruritic disorders were medicated with naltrexone (1 mg/kg of ...
N. Dodman, Louis Shuster, Stephen D. White, Michael H. Court, Denise Parker, Ross Dixon   +5 more
semanticscholar   +1 more source