Results 211 to 220 of about 560,117 (294)

STRUCTURAL FEATURES ASSOCIATED WITH NARCOTICS AND NARCOTIC ANTAGONISTS

Neuropharmacology, 1975
Viminol shares many pharmacological properties of the traditional narcotics, but it differs from the latter because it has an extremely reduced capacity for producing physical dependence. This chapter discusses the types of pharmacological activity related to the structural features of the Viminol stereoisomers.
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Narcotic Antagonists: A Reasonable Method of Treating Narcotic Dependency

International Journal of the Addictions, 1975
Historically, narcotic dependence has been treated primarily by substituting one narcotic drug for another. One alternative chemical treatment for narcotic dependency is through the use of a narcotic antagonist. The present study involves the observed side effects and outcome results of treating 40 male heroin addicts with the narcotic antagonist ...
Kenneth G. Schooff, Ronald G. Hersch, John Keegan   +2 more
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On the ability of narcotic antagonists to produce the narcotic cue.

The Journal of Pharmacology and Experimental Therapeutics, 1976
The ability of narcotic antagonists to produce the narcotic cue was investigated in rats trained to discriminate fentanyl (0.04 mg/kg) from solvent. The partial antagonists pentazocine, cyclazocine and nalorphine were found to possess narcotic cuing activity whereas naloxone lacked any such action at doses up to 160 mg/kg.
F C, Colpaert, C J, Niemegeers, P A, Janssen   +2 more
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Community Outcome on Narcotic Antagonists [PDF]

, 1979
As described at the outset of this book, there were two general goals of this research program: (1) a multivariate assessment of blocked and unblocked heroin consumption in order to characterize the nature of opioid reinforcement and (2) an approach to developing and evaluating narcotic antagonist treatment for the individual addict.
Steven M. Mirin, Fred Zackon, Roger E. Meyer   +2 more
openaire   +1 more source

Microelectrometric titration measurement of the pKa's and partition and drug distribution coefficients of narcotics and narcotic antagonists and their pH and temperature dependence.

Journal of Medicinal Chemistry, 1975
J. J. Kaufman, N. Semo, W. S. Koski
semanticscholar   +1 more source

New structural concepts for narcotic antagonists defined in a 4-phenylpiperidine series

Nature, 1978
D. Zimmerman, R. Nickander, J. Horng, D. Wong   +3 more
semanticscholar   +1 more source

Use of Writhing Test for Evaluating Analgesic Activity of Narcotic Antagonists

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine, 1965
H. Blumberg, P. Wolf, H. B. Dayton
semanticscholar   +1 more source

Narcotic and Narcotic Antagonist Analgesics

Annual Review of Pharmacology, 1967
L S Harris, H F Fraser
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Recent Progress in Research on Narcotic Antagonists

1976
In Volume 8 of this series Archer and Harris [7] reviewed the chemistry and pharmacology of narcotic antagonists. Since that time research in this field has increased enormously as evidenced by the fact that in the decade 1962–72 over 500 references to pentazocine have appeared in the literature.
William F. Michne, Sydney Archer
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Opioid analgesics and narcotic antagonists

, 2014
J. Aronson
semanticscholar   +1 more source