Results 71 to 80 of about 13,200 (250)

Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]

open access: yes, 2017
A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow   +8 more
core   +1 more source

Carbogen Inhalation Therapy for Epileptic Seizures: Mechanisms, Evidence, and Future Directions

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
Carbogen, a low‐dose CO2/O2 mixture, modulates brain pH to suppress hyperexcitability through rapid and reversible pH‐dependent mechanisms distinct from conventional antiseizure medications (ASMs). Preclinical and small clinical studies show efficacy in focal and absence seizures, whereas variable responses in other types highlight the need for ...
Li Wang   +5 more
wiley   +1 more source

Identification of Tetrahydrocannabidiol Metabolites in Human Urine

open access: yesDrug Testing and Analysis, Volume 17, Issue 12, Page 2333-2346, December 2025.
The detection of Phase I and II metabolites of tetrahydrocannabidiol (H4CBD) in urine after oral ingestion of 25‐mg H4CBD by a volunteer is described. The proposed metabolite structures are based on ESI+ spectra recorded by HPLC‐HRMS and EI spectra after trimethylsilylation recorded by GC–MS.
Willi Schirmer   +3 more
wiley   +1 more source

Моделирование диффузионных напряжений, наведенных психоактивными веществами, в кровеносных сосудах биомеханической системы [PDF]

open access: yes, 2008
Теоретичні та числові дослідження даної роботи пов’язані з урахуванням впливу явища переносу психоактивної речовини та дифузійного укорочення кров’яних судин в розрахунках залежних від часу розподілень напружень, наведених психоактивною речовиною, в кров’
Гончарова, Г. В.   +3 more
core  

A Review of Exercise Interventions for Rehabilitation in Drug‐Dependent Individuals

open access: yesAddiction Biology, Volume 30, Issue 12, December 2025.
The analysis of 39 core studies indicates that diverse exercise interventions have varying positive effects across different dimensions for various addiction populations. Exercise can exert beneficial impacts on the neurobiological mechanisms, as well as physiological and psychological aspects, of individuals with drug addiction.
Qinghua He   +8 more
wiley   +1 more source

Exploring Goal‐Concordant Medication Use Among VA Community Living Center Residents With Dementia

open access: yesJournal of the American Geriatrics Society, Volume 73, Issue 12, Page 3738-3746, December 2025.
ABSTRACT Background Documentation of patient goals and preferences within medical records has the potential to align medication use with goals of care (GoC) and individualize medication appropriateness criteria. We characterized patient and surrogate‐expressed GoC for older Veterans living with dementia and explored concordance with medication use ...
Joshua D. Niznik   +11 more
wiley   +1 more source

Naloxone inhibits and morphine potentiates. The adrenal steroidogenic response to ACTH [PDF]

open access: yes
The adrenal actions were stereospecific since neither the positve stereoisomer of morphine, nor that of naloxone, had any effect on the adrenal response to exogenous adrenocorticotrophic hormone (ACTH).
Heybach, J. P., Vernikos, J.
core   +1 more source

Profitable insecurities: trade mark law, misleading advertising, and body image perceptions in the United Kingdom

open access: yesJournal of Law and Society, Volume 52, Issue 4, Page 705-729, December 2025.
Abstract This article critically examines how brand names, slogans, and logos registered as United Kingdom (UK) trade marks for weight management solutions, health‐boosting supplements, and cosmetics are used in marketing communications to influence consumer behaviour. The analysis addresses concerns that these trade signs potentially mislead consumers
LUMINITA OLTEANU
wiley   +1 more source

Effect of Naloxone-3-Glucuronide and N -Methylnaloxone on the Motility of the Isolated Rat Colon After Morphine [PDF]

open access: yes, 2018
The effect of the opioid antagonists naloxone-3-glucuronide and N-methylnaloxone on rat colon motility after morphine stimulation was measured. The rat model consisted of the isolated, vascularly perfused colon.
Batista, Catarina   +5 more
core  

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