Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]
A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow +8 more
core +1 more source
Carbogen Inhalation Therapy for Epileptic Seizures: Mechanisms, Evidence, and Future Directions
Carbogen, a low‐dose CO2/O2 mixture, modulates brain pH to suppress hyperexcitability through rapid and reversible pH‐dependent mechanisms distinct from conventional antiseizure medications (ASMs). Preclinical and small clinical studies show efficacy in focal and absence seizures, whereas variable responses in other types highlight the need for ...
Li Wang +5 more
wiley +1 more source
Identification of Tetrahydrocannabidiol Metabolites in Human Urine
The detection of Phase I and II metabolites of tetrahydrocannabidiol (H4CBD) in urine after oral ingestion of 25‐mg H4CBD by a volunteer is described. The proposed metabolite structures are based on ESI+ spectra recorded by HPLC‐HRMS and EI spectra after trimethylsilylation recorded by GC–MS.
Willi Schirmer +3 more
wiley +1 more source
Quantitative studies on the antagonism by naloxone of some narcotic and narcotic‐antagonist analgesics [PDF]
Stephen E. Smits, A.E. Takemori
openalex +1 more source
Моделирование диффузионных напряжений, наведенных психоактивными веществами, в кровеносных сосудах биомеханической системы [PDF]
Теоретичні та числові дослідження даної роботи пов’язані з урахуванням впливу явища переносу психоактивної речовини та дифузійного укорочення кров’яних судин в розрахунках залежних від часу розподілень напружень, наведених психоактивною речовиною, в кров’
Гончарова, Г. В. +3 more
core
A Review of Exercise Interventions for Rehabilitation in Drug‐Dependent Individuals
The analysis of 39 core studies indicates that diverse exercise interventions have varying positive effects across different dimensions for various addiction populations. Exercise can exert beneficial impacts on the neurobiological mechanisms, as well as physiological and psychological aspects, of individuals with drug addiction.
Qinghua He +8 more
wiley +1 more source
Exploring Goal‐Concordant Medication Use Among VA Community Living Center Residents With Dementia
ABSTRACT Background Documentation of patient goals and preferences within medical records has the potential to align medication use with goals of care (GoC) and individualize medication appropriateness criteria. We characterized patient and surrogate‐expressed GoC for older Veterans living with dementia and explored concordance with medication use ...
Joshua D. Niznik +11 more
wiley +1 more source
Naloxone inhibits and morphine potentiates. The adrenal steroidogenic response to ACTH [PDF]
The adrenal actions were stereospecific since neither the positve stereoisomer of morphine, nor that of naloxone, had any effect on the adrenal response to exogenous adrenocorticotrophic hormone (ACTH).
Heybach, J. P., Vernikos, J.
core +1 more source
Abstract This article critically examines how brand names, slogans, and logos registered as United Kingdom (UK) trade marks for weight management solutions, health‐boosting supplements, and cosmetics are used in marketing communications to influence consumer behaviour. The analysis addresses concerns that these trade signs potentially mislead consumers
LUMINITA OLTEANU
wiley +1 more source
Effect of Naloxone-3-Glucuronide and N -Methylnaloxone on the Motility of the Isolated Rat Colon After Morphine [PDF]
The effect of the opioid antagonists naloxone-3-glucuronide and N-methylnaloxone on rat colon motility after morphine stimulation was measured. The rat model consisted of the isolated, vascularly perfused colon.
Batista, Catarina +5 more
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