Results 41 to 50 of about 74,644 (322)

Standards for labelling and storage of anaesthetic medications--an audit [PDF]

, 2009
OBJECTIVE: To check compliance of anaesthetist to current policies set for the use of medication within operation room and for induction room floor stock.
Abbasi, Shemila, Imran, Muhammad, Khan, Fauzia Anis   +2 more
core   +1 more source

Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA

Advanced Science, EarlyView.
Venous thromboembolism (VTE) is a major threat to cancer patients. Cancer‐derived large extracellular vesicles deliver CYBA (p22phox) to neutrophils, triggering reactive oxygen species (ROS) and citrullinated histone H3 (citH3) formation. This drives neutrophil extracellular traps formation (NETosis), elevating VTE risk.
Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Min   +8 more
wiley   +1 more source

GABAB receptor activation contributes to post-surgery cognitive impairments in mice by inducing hippocampal BDNF hypermethylation

Annals of Medicine
Background Clinical observations have shown that brain-derived neurotrophic factor (BDNF) expression is reduced in patients with impaired cognitive function after anaesthesia and surgery. Abnormal epigenetic changes may contribute to this condition.
Tong Wu, Xiao-Yu Sun, Jing Cao, Kun Tong, Jing-Ru Hao, Nan Sun, Can Gao   +6 more
doaj   +1 more source

Density Functional Theory–Spectroscopy Integrated Identification Method Encompassing Experimental and Theoretical Analyses for Designer Drug Stimulants

Advanced Intelligent Systems, EarlyView.
A novel approach integrates gas chromatography‐mass spectrometry with infrared, Raman, and nuclear magnetic resonance spectroscopy plus density functional theory to detect synthetic drugs. Quantum hyperpolarization further boosts NMR sensitivity for low‐concentration samples, improving detection accuracy in complex mixtures and offering promising ...
Keunhong Jeong, Youngjoon Jeon, Sein Min, Tae In Ryu, Young Wook Yoon, Yoonjae Cho, Seung‐Ryul Hwang, Hye Jin Jeong, Sung Soo Kim   +8 more
wiley   +1 more source

Systematic Literature Review of Spinal Cord Stimulation in Patients With Chronic Back Pain Without Prior Spine Surgery

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objective Low back pain is the leading cause of disability worldwide and one of the most common reasons for seeking healthcare. Despite numerous care strategies, patients with low back pain continue to exhibit poor outcomes. Spinal cord stimulation (SCS) is an evidence‐based therapeutic modality for patients with failed back surgery syndrome ...
Jan M. Eckermann, Julie G. Pilitsis, Christopher Vannaboutathong, Belinda J. Wagner, Rose Province‐Azalde, Markus A. Bendel   +5 more
wiley   +1 more source

Contribution of Addictovigilance data to assess adverse‐events linked to psychoactive substances in children and adolescents

British Journal of Clinical Pharmacology, EarlyView.
Aims We sought to characterize adverse events and deaths associated with the use of psychoactive substances in children and adolescents. Methods Two French Addictovigilance databases were analysed: spontaneous reports and deaths over the period 2016–2021, in subjects aged 10–<18 years. An unsupervised classification was implemented on consumption data (
Hélène Peyrière, Anne Batisse, Nathalie Fouilhé Sam‐Laï, Amélie Daveluy, Christine Fournier‐Choma, Sylvie Deheul, Cécile Chevalier, Clémence Lacroix, Valérie Gibaja, Aurélie Aquizerate, Stéphanie Pain, Emilie Jouanjus, Marie‐Christine Picot, Erika Nogue   +13 more
wiley   +1 more source

Neuronal excitation-inhibition imbalance in the basolateral amygdala is involved in propofol-mediated enhancement of fear memory

Communications Biology
Posttraumatic stress disorder (PTSD) is associated with glutamatergic neuron hyperactivation in the basolateral amygdala (BLA) brain area, while GABAergic interneurons in the BLA modulate glutamatergic neuron excitability.
Chen Chen, Shuai Li, Yue Zhou, Hui Huang, Jia-Tao Lin, Wei-Feng Wu, Yong-Kang Qiu, Wei Dong, Jie Wan, Qiang Liu, Hui Zheng, Yu-Qing Wu, Cheng-Hua Zhou   +12 more
doaj   +1 more source

THE EFFECT OF NARCOTIC AND NARCOTIC-ANTAGONIST DRUGS IN THE NEWBORN RABBIT

British Journal of Anaesthesia, 1976
The newborn rabbit responds to acute anoxia, as a result of breathing nitrogen, with successive periods of dyspnoea, primary apnoea, gasping and terminal apnoea. Pethidine caused an increase in the period of primary apnoea and a decrease in the duration and rate of gasping.
G. W Stephen, L. V Cooper, D Harvey
openaire   +3 more sources

The prevalence of polypharmacy increases with age among patients with inflammatory bowel disease: A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims Polypharmacy is common in adult patients with inflammatory bowel disease (IBD). This study aims to quantify medication prescriptions and estimate the risk of polypharmacy over time in older adults with IBD. Methods In a nationwide cohort of adult incident IBD patients from 1 April 1996, to 31 December 2019, we examined medication prescriptions ...
Ken Lund, Jesper Ryg, Torben Knudsen, Jens Kjeldsen, Jan Nielsen, Sonia Friedman, Jimmy K. Limdi, Bente Mertz Nørgård   +7 more
wiley   +1 more source

Gut microbes–spinal connection is required for itch sensation

Gut Microbes
The gut microbiota has been linked to a number of neurological disorders. However, it is unclear whether the gut microbiota is involved in the genesis of chronic itch, a refractory condition that afflicts patients both physically and mentally.
Tong Jin, Si-Yuan Li, Hong-Li Zheng, Xiao-Dan Liu, Yue Huang, Gan Ma, Ya-Xuan Zhao, Xiao-Tian Zhao, Li Yang, Qi-Hui Wang, Hong-Jun Wang, Chengyong Gu, Zhiqiang Pan, Fuqing Lin   +13 more
doaj   +1 more source