Results 61 to 70 of about 23,788 (138)

MOTS-c is an effective target for treating cancer-induced bone pain through the induction of AMPK-mediated mitochondrial biogenesis

open access: yesActa Biochimica et Biophysica Sinica
Bone cancer pain (BCP), due to cancer bone metastasis and bone destruction, is a common symptom of tumors, including breast, prostate, and lung tumors. Patients often experience severe pain without effective treatment.
Yang Long   +7 more
doaj   +1 more source

Snapshot of narcotic drugs and psychoactive substances in Kuwait: analysis of illicit drugs use in Kuwait from 2015 to 2018. [PDF]

open access: yesBMC Public Health, 2021
Al-Matrouk A   +7 more
europepmc   +1 more source

Divergent input patterns to the central lateral amygdala play a duet in fear memory formation

open access: yesiScience
Summary: Somatostatin (SOM)-expressing neurons in the central lateral amygdala (CeL) are responsible for fear memory learning, but the circuit and molecular mechanisms underlying this biology remain elusive.
Jing-hua Gao   +9 more
doaj   +1 more source

Efficacy of transcranial direct current stimulation for improving postoperative quality of recovery in elderly patients undergoing lower limb major arthroplasty: a randomized controlled substudy

open access: yesFrontiers in Neurology
BackgroundPrevious studies have demonstrated improvements in motor, behavioral, and emotional areas following transcranial direct current stimulation (tDCS), but no published studies have reported the efficacy of tDCS on postoperative recovery quality in
Mingshu Tao   +23 more
doaj   +1 more source

On the issue of establishing extraterritorial jurisdiction over transnational crimes in the sphere of illegal trafficking in narcotic drugs and similar substances: international and legal analysis

open access: yesЮридический вестник Самарского университета
The increasing level of drug addiction in the world community requires the Russian Federation to coordinate measures aimed at combating the illegal trafficking of narcotic drugs and similar substances. The intensifying transnational nature of crime makes
I. Yu. Belyaev
doaj   +1 more source

Managing dual disorders: a statement by the Informal Scientific Network, UN Commission on Narcotic Drugs. [PDF]

open access: yesWorld Psychiatry, 2020
Volkow ND   +9 more
europepmc   +1 more source

Carrier-free nanomedicines: Mechanisms of formation and biomedical applications

open access: yesGiant
In recent years, significant advancements in nanotechnology have yielded remarkable improvements in biomedical applications. Nanocarriers, harnessed from the principles of nanotechnology, have garnered widespread utilization in medicine delivery and ...
Xinrui Dong   +4 more
doaj   +1 more source

University proceedings. Volga region. Social sciences

open access: yesИзвестия высших учебных заведений. Поволжский регион: Общественные науки
Background. The relevance of the problem under study is that the problems asso-ciated with the qualification and proof in cases of illegal drug production often arise due to different interpretations of the provisions of criminal law.
E.V. Bityutskiy, N.I. Svechnikov
doaj   +1 more source

The microglial innate immune receptor TREM2 participates in fear memory formation through excessive prelimbic cortical synaptic pruning

open access: yesFrontiers in Immunology
IntroductionFear memory formation has been implicated in fear- and stress-related psychiatric disorders, including post-traumatic stress disorder (PTSD) and phobias.
Le-le Zhang   +15 more
doaj   +1 more source

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