Results 151 to 160 of about 17,818 (203)

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang   +10 more
wiley   +1 more source

Interface‐Directed High Fluorescence Efficiency Two‐Dimensional Molecular Crystals With Surface‐Exposed Active Sites

open access: yesAdvanced Science, Volume 13, Issue 54, 28 September 2026.
Here, we designed the Me‐FBSe molecule and prepared a two‐dimensional molecular crystal via liquid‐liquid interface assembly. The crystal preserves the high photoluminescence quantum while simultaneously ensuring the high‐density surface exposure of active sites.
Shuya Liu   +6 more
wiley   +1 more source

Undetectable Hydroxyurea Levels in the Majority of Sickle Cell Disease Patients, Especially in Young Children

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2297-2310, September 2026.
ABSTRACT Hydroxyurea (HU) is the most widely prescribed disease‐modifying treatment in sickle cell disease (SCD), though treatment responses vary due to metabolism and adherence. We examined HU blood levels and treatment response in patients with homozygous sickle cell disease (HbSS).
Sigrid van der Veen   +26 more
wiley   +1 more source

Lidocaine Combined With Platelet‐Rich Plasma for Stellate Ganglion Block in Chronic Migraine: A Multicenter, Prospective, Propensity Score‐Matched Cohort Study

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objectives To explore the association of stellate ganglion block with platelet‐rich plasma plus lidocaine with clinical outcomes in adults with chronic migraine, in comparison to lidocaine alone. Methods This multicenter prospective exploratory study enrolled 200 adults with chronic migraine scheduled for stellate ganglion block across three ...
Lu Liu   +5 more
wiley   +1 more source

Vimseltinib for patients with tenosynovial giant cell tumor: A multicenter, open‐label, phase 2 trial

open access: yesCancer, Volume 132, Issue 17, 1 September 2026.
Abstract Background Tenosynovial giant cell tumor (TGCT) is a locally aggressive neoplasm caused by dysregulation of the colony‐stimulating factor 1 (CSF1) gene. Patients report substantial pain, stiffness, and declining physical function; those whose disease is not amenable to surgery require systemic therapy.
Silvia Stacchiotti   +31 more
wiley   +1 more source

Smoking Abstinence Elicits Hyperalgesia: Neural Mechanism, Clinical Implications, and Pharmacological Managements

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
The cycle between nicotine use and pain modulation. Cigarette smoking leads to nicotine entering the body, which binds to nicotinic acetylcholine receptors (nAChRs) in the brain, triggering the release of different neurotransmitters, including dopamine (DA), norepinephrine (NE), serotonin (5‐HT), and GABA.
Shan‐shan Hu   +3 more
wiley   +1 more source

Synergistic Photo‐Electro‐Fenton Oxidation of Antibiotics Using a Ferrocene‐Functionalized MXene (Ti3C2Tx) Electrode

open access: yesENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 5, September 2026.
2D MXene (Ti3C2Tx)‐based electrode setup for hybrid photo‐electro‐Fenton degradation of antibiotic (tetracycline). The persistence of antibiotics such as tetracycline in aquatic systems poses severe environmental and health risks by potential antimicrobial resistance.
Durga Sankar Vavilapalli   +8 more
wiley   +1 more source

Preliminary Investigation of Disorders of Gut–Brain Interaction and Their Associations With Psychological Flexibility and Daily Functioning in People With Fibromyalgia

open access: yesEuropean Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background A substantial proportion of people with fibromyalgia also experience comorbid disorders of gut–brain interaction (DGBIs), which can lead to considerable personal and societal burdens. However, evidence regarding the implications of this comorbidity remains limited.
Lin Yu   +3 more
wiley   +1 more source

Association Between Opium Consumption and Lipid Profile: A Systematic Review and Meta‐Analysis of Observational Studies

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Opium, traditionally used for its analgesic and sedative properties, has been widely consumed. Given the conflicting evidence regarding its association with lipid profiles, the present study was conducted to investigate the association between opium consumption and lipid profile parameters.
Fatemeh Zahra Gafuori Fard   +3 more
wiley   +1 more source

Serosurvey of Toxoplasmosis Among Drug Users in Fars Province, Southern Iran: A Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Toxoplasma gondii is a widespread zoonotic protozoan that poses significant health risks, particularly to immunocompromised individuals. Although generally asymptomatic, toxoplasmosis can lead to severe neurological complications and behavioral disorders.
Mohammad Reza Cheraghi   +10 more
wiley   +1 more source

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