Results 1 to 10 of about 149,571 (273)

Nasal Residence Depending on the Administered Dosage Form: Impact of Formulation Type on the In Vivo Nasal Retention Time of Drugs in Rats [PDF]

Pharmaceutics
Background/Objectives: The precise control of drug absorption through the nasal mucosa following intranasal administration can be achieved through optimal formulation development that considers the nasal retention properties of the administered dosage ...
Daisuke Inoue, Yoshihiro Seto, Hideto To
doaj   +8 more sources

Study of surfactants influence on the noopept releasing from the nasal dosage form

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
The nasal route of drug administration, as is well known, is characterized by some advantages: absorption rate and rapid onset of therapeutic effect, availability of drug delivery without hepatic first-pass elimination, it is suitable and easily ...
B. S. Burlaka, I. F. Bielenichev, V. V. Hladyshev   +2 more
doaj   +7 more sources

Study of excipients influence on the noopept releasing from the nasal dosage form

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The development of medicines for fast delivery is the actual direction of modern pharmacy. In this connection, the nasal route of drug administration is perspective and has some advantages. The greater permeability of nasal mucosa with large surface area
B. S. Burlaka, I. F. Bielenichev, V. V. Hladyshev   +2 more
doaj   +7 more sources

STUDY OF REOLOGICAL PROPERTIES OF CAPTOPRIL NASAL DOSAGE FORM

Zaporožskij Medicinskij Žurnal, 2013
The aim of this work was to study properties of ACE inhibitor captopril semisolid dosage form which was developed on the department of technology of medication in Zaporozhye State Medical University. The complex of physico-chemical, pharmacotechnological
Аlmochаmаd Guмаа Аbdullах, V. V. Gladyishev, B. S. Burlaka, N. N. Маlеckiy   +3 more
doaj   +4 more sources

The study of consistent properties of the vasopressin nasal dosage form

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Evaluation of consistent properties is an important and integral part of investigations on the creation of semisolid nasal pharmacotherapeutic agents. The aim of this work is the study of consistent properties of developed nasal semisolid dosage form ...
Al Nukarii Abdulkarim, A. L. Drozdov, A. P. Lysyanskaya   +2 more
doaj   +6 more sources

Development and evaluation of a composite dosage form containing desmopressin acetate for buccal administration

International Journal of Pharmaceutics: X, 2021
Desmopressin acetate (DDAVP) is an oligopeptide indicated for the treatment of primary nocturnal enuresis, for example. The poor oral bioavailability of DDAVP accelerated a shift to alternative routes of administration like nasal and oromucosal, whereby ...
Dina Kottke, Bjoern B. Burckhardt, Tanja C. Knaab, Jörg Breitkreutz, Björn Fischer   +4 more
doaj   +3 more sources

In situ gelling, bioadhesive nasal inserts for extended drug delivery: In vitro characterization of a new nasal dosage form

European Journal of Pharmaceutical Sciences, 2006
The purpose of this study was the preparation and characterization of sponge-like, in situ gelling inserts based on bioadhesive polymers. Hydrophilic polymers (carrageenan, Carbopol, chitosan, hydroxypropyl methylcellulose (HPMC) K15M and E5, sodium alginate, sodium carboxy methylcellulose (NaCMC), polyvinyl pyrrolidone (PVP) 90, xanthan gum) were ...
Roland Bodmeier
exaly   +4 more sources

Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form

Future Journal of Pharmaceutical Sciences, 2021
Background A simple, robust, precise, and an accurate HPLC method was established for simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from a nasal spray dosage form. The effective separation was obtained by injecting 10 μl
Bhaskar Musmade, Prashant Sanatan, Surbhi Lokhande, Shrikant Kulkarni, Shrinivas Bhope, Sriram Padmanabhan, Amol Pachpinde, Kishan Lohar   +7 more
doaj   +2 more sources

Novel liquid-based approaches for transmucosal drug delivery [PDF]

Acta Pharmaceutica Sinica B
Advancements in drug discovery, such as artificial intelligence, computational technology, and combinatorial chemistry, have led to numerous new promising drug candidates.
Daniélle van Staden, Hendrik J.R. Lemmer, Wilna Liebenberg, Josias H. Hamman   +3 more
doaj   +2 more sources

Comparison of Modern In Vitro Permeability Methods with the Aim of Investigation Nasal Dosage Forms [PDF]

Pharmaceutics, 2021
Nowadays, the intranasal route has become a reliable alternative route for drug administration to the systemic circulation or central nervous system. However, there are no official in vitro diffusion and dissolution tests especially for the investigation of nasal formulations.
Csilla Bartos, Piroska Szabo-Revesz, Tamás Horvath   +2 more
exaly   +5 more sources