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Harnessing the Therapeutic Potential of Dillenia indica: An Overview of Recent Dosage Form Developments

Current Drug Discovery Technologies
Dillenia indica, commonly known as Elephant Apple, is a significant medicinal plant found in Assam, North-East India. This evergreen shrub or small to medium-sized tree possesses not only tasty components but also a plethora of beneficial therapeutic ...
Kalyani Pathak
exaly   +2 more sources

Selecting the Correct Dosage Form for Topical Nasal Decongestants: An Expert Opinion

Journal of The Association of Physicians of India
Nasal congestion is a bothersome symptom of allergic rhinitis (AR), common cold, and sinusitis, and can significantly impact quality of life (QoL). In options available for managing nasal congestion, oral decongestants have a slower onset of action compared with topical nasal decongestants like oxymetazoline and xylometazoline, which have an onset of ...
Samir, Bharagava   +5 more
openaire   +3 more sources

Nasal absorption of propranolol from different dosage forms by rats and dogs

Journal of Pharmaceutical Sciences, 1980
The blood levels of propranolol in rats and dogs were compared after the administration of nasal, intravenous, and oral solutions. The results indicate that the blood drug levels after nasal and intravenous administration were identical, but the oral administration resulted in considerably lower blood levels.
Shinichiro Hirai
exaly   +3 more sources

Evaluation of sedative effects of an intranasal dosage form containing saffron, lettuce seeds and sweet violet in primary chronic insomnia: A randomized, double-dummy, double-blind placebo controlled clinical trial.

Journal of Ethnopharmacology, 2020
ETHNOPHARMACOLOGICAL RELEVANCE Traditional Persian Medicine (TPM) has been established as a valuable source of medicinal plants for the treatment of insomnia for thousands of years.
Z. Taherzadeh   +5 more
semanticscholar   +1 more source

Pharmacodynamic Comparison of a Nasal Formulation of Verapamil and Intravenous and Oral Dosage Forms

Drug Development and Industrial Pharmacy, 1996
AbstractThe nasal route has been shown to be effective for the administration of numerous drugs in order to improve drug bioavailability. A nasal gel of verapamil hydrochloride was formulated and evaluated pharmacodynamically in humans, using electrocardiographic results, with comparison to oral and IV routes.
Yazan, Y, Özer, AY, Erol, K
openaire   +2 more sources

[Development of nasal dosage form of oxatomide for rhinitis].

Arerugi = [Allergy], 2004
The possibility of oxatomide as the nasal dosage drug for the therapy of nasal allergy was studied. Oxatomide was well absorbed from the nasal cavity, indicating a high permeability to nasal epithelial layer after nasal administration. Acidic pH condition further enhanced the permeation of oxatomide across Caco-2 monolayers, due to the high solubility ...
Tomoyuki, Furubayashi   +4 more
openaire   +1 more source

COMPARATIVE SURFACE TENSION STUDY OF ORAL, NASAL, AND OPHTHALMIC LIQUID DOSAGE FORMS AVAILABLE IN IRAQ

Asian Journal of Pharmaceutical and Clinical Research
Objective: Surface tension at the liquid–air interface is an important physicochemical property that affects spreading, retention, and interaction of pharmaceutical liquids with biological surfaces.
Maryam Alaayedi   +3 more
semanticscholar   +1 more source

Nasal distribution of radioactive drug administered using two dosage forms.

European journal of drug metabolism and pharmacokinetics, 1992
The deposition patterns of 99mtechnetium labelled disodium cromoglycate particles administered either from a metered dose aerosol with a conventional nasal adaptor or from a dry powder nasal inhaler were studied using gamma camera. Disodium cromoglycate particles were firstly labelled with 99mTc using the spray drying technique.
P, Vidgren   +4 more
openaire   +1 more source

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