Results 141 to 150 of about 474,986 (351)

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Vasovagal attack during anterior nasal packing in patients with epistaxis

International Archives of Otorhinolaryngology, 2008
Introduction: The incident of fainting during nasal packing to manage epistaxis is not so uncommon. Objective: To observe the effect of anterior nasal packing on blood pressure and heart rate, during the management of epistaxis.
Roychowdhary, Paresh, Pramanik, Tapas, Adhikari, Prakash   +2 more
doaj  

Tualang Honey-impregnated Nasal Pack in Endoscopic Sinus Surgery Reduces Post-operative Inflammation and Bacterial Growth

B-ENT
Background: To compare the efficacy of nasal packing using nasopore impregnated with tualang honey (THP) in middle meatal packing to contralateral saline-impregnated nasal packing (SP) in endoscopic sinus surgery (ESS).
Muhd Faiz Bin Zulkifli, Primuharsa Putra Bin Sabir Husin Athar, Mohd Ridzo Bin Mahmud, Ruszymah Binti Hj Idrus, Isa Bin Mohamad Rose, Aminuddin Bin Saim   +5 more
doaj   +1 more source

Nasal Septal Suture Technique versus Nasal Packing after Septoplasty: A Prospective Comparative Study

, 2018
Nasal packing materials are widely used in endonasal surgery, including septoplasty, turbinoplasty and paranasal sinus surgery. They are also used to prevent synechiae and haematoma formation, to support septal flap apposition, and to close dead space ...
Shambulinga Killera, Deepthi Padmanabhan, B. Viswanatha   +2 more
semanticscholar   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Biodegradable nasal packings for endoscopic sinonasal surgery: a systematic review and meta-analysis.

PLoS ONE, 2014
ObjectivesTo assess biodegradable nasal packing effectiveness for improving postoperative symptoms and mucosal healing after endoscopic sinonasal surgery as compared with conventional/non-packing groups.MethodsRelevant articles were searched on PubMed ...
Maoxiao Yan, Dandan Zheng, Ying Li, Qiaoli Zheng, Jia Chen, Beibei Yang   +5 more
doaj   +1 more source

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

Efficacy of Triamcinolone Nasal Packing on Post-Operative Outcome in Endoscopic Sinus Surgery. [PDF]

Indian J Otolaryngol Head Neck Surg, 2023
Gajendran A, Saravanam PK, Jayagandhi S.
europepmc   +1 more source

Full Issue: Volume 13, Issue 1 - Winter 2018 [PDF]

, 2018
Full Issue: Volume 13, Issue 1 - Winter ...

core   +1 more source

QUILTING, AS AN ALTERNATIVE TO NASAL PACKING,OUR EXPERIENCE AT A GOVERNMENT DISTRICTHOSPITAL IN NORTH INDIA

, 2022
Vertika Tewari
openalex   +1 more source