Results 81 to 90 of about 375,973 (338)

Nasopharyngeal disease in cats:2. Specific conditions and their management [PDF]

, 2012
Practical relevance: Nasopharyngeal disease is a common presenting problem in feline medicine. Clinical challenges: The management of feline nasopharyngeal disease can be challenging at a number of levels. In many cases, a specific diagnosis may remain
Gunn-Moore, Danièlle, Reed, Nicki
core   +1 more source

Effect and Threshold of Endoscopic Findings for CRS Control Status and Long‐Term Outcome Prediction

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background EPOS 2020 defined chronic rhinosinusitis (CRS) disease control using patient symptoms and medication usage but endoscopic findings were considered optional. The effect of adding endoscopic features, an appropriate threshold, and their association with present or future symptom control have not been studied.
Steven Chun‐Kang Liao, Aditi Agarwal, Junqin Bai, Zhidi Luo, Siyuan Dong, Regan L. Harmon, Brooke N. Gleason, Julia Huang, David B. Conley, Kevin C. Welch, Stephanie Shintani‐Smith, Robert C. Kern, Atsushi Kato, Lutfiyya N. Muhammad, Bruce K. Tan   +14 more
wiley   +1 more source

The Role of Platelet-Derived Growth Factor in the Pathogenesis of Sinonasal Polyps: Immunohistochemical Assessment in Epithelial, Subepithelial and Deep Layers of the Mucosa [PDF]

Clinical and Experimental Otorhinolaryngology, 2013
ObjectivesThe aim of this study is to investigate the role of platelet-derived growth factor (PDGF) in the pathogenesis of sinonasal polyps.MethodsStudy group (groups 1-3) consisted of nasal polyp samples of patients with sinonasal polyps and the control
Nuray Bayar Muluk, Osman Kürşat Arıkan, Pınar Atasoy, Rahmi Kılıç, Eda Tuna Yalçinozan   +4 more
doaj   +1 more source

Staphylococcal enterotoxin B influences the DNA methylation pattern in nasal polyp tissue : a preliminary study [PDF]

, 2013
Staphylococcal enterotoxins may influence the pro-inflammatory pattern of chronic sinus diseases via epigenetic events. This work intended to investigate the potential of staphylococcal enterotoxin B (SEB) to induce changes in the DNA methylation pattern.
Bachert, Claus, De Meyer, Tim, Denil, Simon, Perez Novo, Claudina, Trooskens, Geert, Van Cauwenberge, Paul, Van Criekinge, Wim, Zhang, Luo, Zhang, Yuan   +8 more
core   +2 more sources

Early and Sustained Improvements in Sense of Smell With Tezepelumab Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyps (WAYPOINT)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Loss of smell is a principal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), affecting health‐related quality of life and posing a safety hazard. Methods WAYPOINT (NCT04851964), a phase 3, multicenter trial in adults with uncontrolled CRSwNP, randomized patients 1:1 to receive tezepelumab 210 mg or placebo ...
Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose   +14 more
wiley   +1 more source

Dexamethasone Induces Apoptosis of Nasal Polyp-Derived Tissue Cultures Through JNK and p38 MAPK Activation [PDF]

Clinical and Experimental Otorhinolaryngology, 2014
ObjectivesGlucocorticoids, such as dexamethasone (DEX), increase apoptosis in a variety of white cells in nasal polyps and apoptosis is an important factor in the resolution of inflammation.
Tae-Hoon Lee, Jung Gwon Nam, Ho Min Lee, Bo-Young Kim, Myung-Koo Kang, Woo Yong Bae, Dae Young Hur, Seong Kook Park   +7 more
doaj   +1 more source

Lipopolysaccharide Induces Pro-Inflammatory Cytokines and MMP Production via TLR4 in Nasal Polyp-Derived Fibroblast and Organ Culture

PLoS ONE, 2014
Nasal polyposis is characterized by persistent inflammation and remodeling in sinonasal mucosa. Toll-like receptors (TLRs) play a role in the innate immune response to microbes in the sinonasal cavity.
Jung‐Sun Cho, Ju-hyung Kang, Ji-Young Um, In-Hye Han, I. Park, Heung-Man Lee   +5 more
semanticscholar   +1 more source

Prostaglandin E2 Induces IL-6 and IL-8 Production by the EP Receptors/Akt/NF-κB Pathways in Nasal Polyp-Derived Fibroblasts

Allergy Asthma and Immunology Research, 2014
Purpose Interleukin 6 (IL-6) and IL-8 participate in the pathogenesis of chronic rhinosinusitis with nasal polyps, and their levels are increased by prostaglandin E2 (PGE2) in different cell types.
Jung‐Sun Cho, In-Hye Han, H. Lee, Heung-Man Lee   +3 more
semanticscholar   +1 more source

The role of powered instrumentation in the removal of antrochoanal polyps: a 10-Year Review [PDF]

, 2009
Antrochoanal polyps are rare lesions. We report a series of 40 consecutive cases of antrochoanal polyps treated in our tertiary centre over a period of ten years between May 1998 and April 2008. The median age of the patients was 37 years.
Gendeh BS,, Mohd Razif MY,, Mohd Tahir J,   +2 more
core  

Dysregulation of U12‐Type Splicing in Lupus Neutrophils

Arthritis &Rheumatology, Accepted Article.
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco, Binod Regmi, Carmelo Carmona‐Rivera, Yudong Liu, Xiantao Wang, Philip M. Carlucci, Monica M. Jackson, Zerai Manna, Sarfaraz Hasni, Markus Hafner, Hong‐Wei Sun, Mariana J. Kaplan   +11 more
wiley   +1 more source