Importance of Smell Loss to Patients With Chronic Rhinosinusitis With Nasal Polyps: Options for Management and Recovery. [PDF]
Higgins TS +9 more
europepmc +1 more source
From Nerves to Vessels: Unmasking Churg‐Strauss Behind Polyneuropathy
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA), formerly Churg‐Strauss vasculitis, is a rare systemic autoimmune disease. Neurological involvement is a significant complication. This report details a case of EGPA with severe, progressive polyneuropathy and atypical serological findings, highlighting diagnostic challenges and the ...
Hiba Antar +2 more
wiley +1 more source
Dysregulated glycosaminoglycan biosynthesis and retinoid metabolism in chronic rhinosinusitis with nasal polyps: insights from a comprehensive transcriptomic analysis. [PDF]
Nepp N +6 more
europepmc +1 more source
This graphical abstract illustrates the novel ZFP36L1–CAMK2A regulatory axis in chronic rhinosinusitis (CRS) pathogenesis: 1. Molecular initiation: In nasal epithelial cells, the RNA‐binding protein ZFP36L1 (upregulated in CRS) directly binds to AU‐rich elements (AREs) in the 3′‐untranslated region (3′‐UTR) of CAMK2A mRNA, promoting its degradation and
Jiayi Xiong +6 more
wiley +1 more source
Increased LOXL2 facilitates tissue remodeling in eosinophilic chronic rhinosinusitis with nasal polyps. [PDF]
Jiang C, Wang X, Li R, Ni L, Liu X.
europepmc +1 more source
Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi +6 more
wiley +1 more source
Inhibition of Airway Epithelial CTSC Attenuates Type 2 Inflammation: Implications for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps. [PDF]
Li X +8 more
europepmc +1 more source
Menetrier's: A pediatric chronic state of disease with a possible heritable form
Abstract Menetrier's disease (MD) is a rare, typically transient, hypertrophic gastropathy with under 1000 adult cases and 50 pediatric cases known worldwide. Pediatric cases most often present with an infectious etiology. We present a case of a teenage male expressing a chronic state of disease without infectious origin.
MariaElena Terzis +2 more
wiley +1 more source
Nasal cytology in the rhinology-allergy clinic: From rhinitis to chronic rhinosinusitis with nasal polyps (CRSwNP). [PDF]
Gelardi M.
europepmc +1 more source
Elexacaftor–Tezacaftor–Ivacaftor Reduces Revision Sinus Surgery in People With Cystic Fibrosis
Elexacaftor–tezacaftor–ivacaftor (ETI) was associated with a significant decrease in the frequency and rate of endoscopic sinus surgeries in patients with cystic fibrosis. These findings suggest an improvement in CF‐related chronic rhinosinusitis outcomes following ETI and may influence future CF treatment decisions.
Amy Lin +6 more
wiley +1 more source

