Results 201 to 210 of about 48,438 (295)

Demographic and Comorbidity Associations With Disease Severity and Bony Dehiscence in AFRS

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objective(s) The purpose of this study is to explore and describe possible demographic factors and comorbidities as they relate to disease severity of allergic fungal rhinosinusitis (AFRS) on initial presentation. Methods A retrospective review was conducted on 153 patients with AFRS seen at a tertiary care center. Demographics, comorbidities,
Diana Bigler   +6 more
wiley   +1 more source

Diagnostic Performance of a Large Language Model (ChatGPT‐4o) in Chronic Rhinosinusitis CT Scan Interpretation

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Background Large language models (LLMs), such as ChatGPT, are increasingly utilized by physicians for clinical decision support due to their ease of use and versatility. However, their performance in diagnostic imaging remains largely untested.
Mohammed Sulaiman Alsayyari   +4 more
wiley   +1 more source

Obesity and New‐Onset Asthma Risk in Chronic Rhinosinusitis: A Population‐Based Cohort Study

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
This population‐based cohort study used the TriNetX U.S. Collaborative Network to evaluate the association between body mass index and subsequent asthma outcomes among adults with chronic rhinosinusitis. Elevated BMI was associated with a dose‐dependent increase in risk of new‐onset asthma and asthma exacerbations across 1‐, 2‐, and 5‐year follow‐up ...
Austin J. Lee   +2 more
wiley   +1 more source

Viral Detection and Clinical Disease Features in Pediatric Chronic Rhinosinusitis

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Objectives Chronic rhinosinusitis (CRS) results from complex host‐environment interactions with microbiome dysbiosis and viral infections postulated to drive inflammation and anatomic remodeling. This study investigates the impact of viral presence on pediatric sinonasal disease and clinical outcomes.
Mary C. Wilding   +7 more
wiley   +1 more source

High Radiological Severity in CRSwNP Is Associated With a Mixed Type 2/Type 3 Epithelial Inflammatory Signature

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
This study demonstrates that high radiological severity in patients with CRSwNP is uniquely characterized by a mixed Type 2 and Type 3 epithelial inflammatory signature. These findings suggest that severe disease involves a complex immune endotype, providing new insights into precision therapeutic strategies for refractory CRSwNP.
Guangfu Xu   +5 more
wiley   +1 more source

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