Dose-dependent IL-29 activation of TLR4 signalling drives eosinophil infiltration in chronic rhinosinusitis with nasal polyps. [PDF]
Zhong Y, Yan H, Zhou Y, Huang N, Li J.
europepmc +1 more source
Demographic and Comorbidity Associations With Disease Severity and Bony Dehiscence in AFRS
ABSTRACT Objective(s) The purpose of this study is to explore and describe possible demographic factors and comorbidities as they relate to disease severity of allergic fungal rhinosinusitis (AFRS) on initial presentation. Methods A retrospective review was conducted on 153 patients with AFRS seen at a tertiary care center. Demographics, comorbidities,
Diana Bigler +6 more
wiley +1 more source
Increased LOXL2 facilitates tissue remodeling in eosinophilic chronic rhinosinusitis with nasal polyps. [PDF]
Jiang C, Wang X, Li R, Ni L, Liu X.
europepmc +1 more source
ABSTRACT Background Large language models (LLMs), such as ChatGPT, are increasingly utilized by physicians for clinical decision support due to their ease of use and versatility. However, their performance in diagnostic imaging remains largely untested.
Mohammed Sulaiman Alsayyari +4 more
wiley +1 more source
Nasal cytology in the rhinology-allergy clinic: From rhinitis to chronic rhinosinusitis with nasal polyps (CRSwNP). [PDF]
Gelardi M.
europepmc +1 more source
Obesity and New‐Onset Asthma Risk in Chronic Rhinosinusitis: A Population‐Based Cohort Study
This population‐based cohort study used the TriNetX U.S. Collaborative Network to evaluate the association between body mass index and subsequent asthma outcomes among adults with chronic rhinosinusitis. Elevated BMI was associated with a dose‐dependent increase in risk of new‐onset asthma and asthma exacerbations across 1‐, 2‐, and 5‐year follow‐up ...
Austin J. Lee +2 more
wiley +1 more source
Inhibition of Airway Epithelial CTSC Attenuates Type 2 Inflammation: Implications for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps. [PDF]
Li X +8 more
europepmc +1 more source
Viral Detection and Clinical Disease Features in Pediatric Chronic Rhinosinusitis
ABSTRACT Objectives Chronic rhinosinusitis (CRS) results from complex host‐environment interactions with microbiome dysbiosis and viral infections postulated to drive inflammation and anatomic remodeling. This study investigates the impact of viral presence on pediatric sinonasal disease and clinical outcomes.
Mary C. Wilding +7 more
wiley +1 more source
This study demonstrates that high radiological severity in patients with CRSwNP is uniquely characterized by a mixed Type 2 and Type 3 epithelial inflammatory signature. These findings suggest that severe disease involves a complex immune endotype, providing new insights into precision therapeutic strategies for refractory CRSwNP.
Guangfu Xu +5 more
wiley +1 more source
Impact of Early Versus Delayed Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyps. [PDF]
Duggal R +4 more
europepmc +1 more source

