Results 21 to 30 of about 22,731 (179)

Risperidone Powder Prepared by Spray Drying Technology for Intranasal Delivery [PDF]

BIO Web of Conferences, 2023
The main objective of this study was to prepare Risperidone (RIS) nasal powder by spray drying method, so as to achieve controlled drug release and high deposition efficiency in the nasal cavity.
Li Ting, Shi Jingyu, Tong Zhengbo, Miao Hao   +3 more
doaj   +1 more source

Comparative study of nasal cavity drug delivery efficiency with different nozzles in a 3D printed model [PDF]

PeerJ
Background Nasal sprays are widely used in treating nasal and sinus diseases; however, there are very few studies on the drug delivery efficiency of nasal sprays.
Shengjian Fang, Xiaoqing Rui, Yu Zhang, Zhangwei Yang, Weihua Wang   +4 more
doaj   +2 more sources

Liquid Film Translocation Significantly Enhances Nasal Spray Delivery to Olfactory Region: A Numerical Simulation Study

Pharmaceutics, 2021
Previous in vivo and ex vivo studies have tested nasal sprays with varying head positions to enhance the olfactory delivery; however, such studies often suffered from a lack of quantitative dosimetry in the target region, which relied on the observer’s ...
Xiuhua April Si, Muhammad Sami, Jinxiang Xi   +2 more
doaj   +1 more source

Nasal Spray Use Technique Among Patients Attending the Out-Patient Department of a Tertiary Care Hospital, Gandaki Province, Nepal

Integrated Pharmacy Research and Practice, 2020
Binita KC, Gulam Muhammad Khan, Niranjan Shrestha School of Health and Allied Sciences, Pokhara University, Kaski, NepalCorrespondence: Binita KCSchool of Health and Allied Sciences, Pokhara University, Kaski, NepalTel +9779846347207 Email kcbinita05 ...
KC B, Khan GM, Shrestha N
doaj  

Nasal Administration and Plasma Pharmacokinetics of Parathyroid Hormone Peptide PTH 1-34 for the Treatment of Osteoporosis

Pharmaceutics, 2019
Nasal delivery of large peptides such as parathyroid 1-34 (PTH 1-34) can benefit from a permeation enhancer to promote absorption across the nasal mucosa into the bloodstream.
Richard G. Pearson, Tahir Masud, Elaine Blackshaw, Andrew Naylor, Michael Hinchcliffe, Kirk Jeffery, Faron Jordan, Anjumn Shabir-Ahmed, Gareth King, Andrew L. Lewis, Lisbeth Illum, Alan C. Perkins   +11 more
doaj   +1 more source

Cluster randomised, controlled, triple-blind trial assessing the efficacy of intranasally administered virus-neutralising bovine colostrum supplement in preventing SARS-CoV-2 infection in household contacts of SARS-CoV-2-positive individuals: a study protocol

Trials, 2022
The SARS-CoV-2 enters into the human body mainly through the nasal epithelial cells. Prevention of SARS-CoV-2 infection at the point of nasal entry is a novel strategy that has the potential to help contain the ongoing pandemic. BioBlock is a nasal spray
Anneli Uusküla, Aime Keis, Karolin Toompere, Anu Planken, Konstantin Rebrov   +4 more
doaj   +1 more source

In Vitro Ciliotoxicity and Cytotoxicity Testing of Repeated Chronic Exposure to Topical Nasal Formulations for Safety Studies

Pharmaceutics, 2021
Certain active drugs and excipients of nasal formulations may impair ciliary function and mucociliary clearance. The ciliary beat frequency (CBF) is a key parameter for determining mucociliary clearance rate, and in vitro assessments of CBF have proven ...
Larisa Tratnjek, Nadica Sibinovska, Katja Kristan, Mateja Erdani Kreft   +3 more
doaj   +1 more source

The effect of intranasal steroid in the treatment of allergic rhinitis with and without oral antihistamine (comparative study)

Advanced Medical Journal, 2022
Backgrounds & objectives: Numerous studies have investigated the efficacies of steroid nasal sprays for adults with allergic rhinitis. However, research on their effectiveness in combination with oral antihistamines is limited.
Moyeser Abdulrahman Yaseen, Salar Majeed Piro   +1 more
doaj   +1 more source

Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction

Advanced Functional Materials, EarlyView.
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch, Sandra Kessler, Simone Ponta, Anna Puiggalí‐Jou, Guoliang Lyu, Killian Flégeau, Anastasiya Martyts, Florian Roth, David Fercher, Filippo M. Rijli, Daniel Simmen, Eva Novoa Olivares, Thomas Linder, Marcy Zenobi‐Wong   +13 more
wiley   +1 more source

Efficacy and safety of fluticasone propionate nasal spray in treatment ofadenoidal hypertrophic snoring in children

Brazilian Journal of Pharmaceutical Sciences, 2023
This study investigatedthe efficacy and safety offluticasone propionate nasal spray in treatment of adenoidal hypertrophic snoring in children.Fifty-six children with adenoidal hypertrophic snoring were enrolled.
Hanzhong Duan, Li Xia, Qing Lan
doaj   +1 more source