Results 11 to 20 of about 60,978 (331)

Management of treatment-resistant depression with esketamine nasal spray: clinical questions for daily practice in Gulf Cooperation Council countries

open access: yesMiddle East Current Psychiatry, 2023
Background There is a high unmet need among patients with treatment-resistant depression (TRD) as treatment with standard therapies is associated with low response and remission rates and high rates of relapse.
Nahida Nayaz Ahmed   +5 more
doaj   +1 more source

Effect of short-course glucocorticoid application on patients with chronic rhinosinusitis with nasal polyps

open access: yesWorld Allergy Organization Journal, 2020
Background: Local and systemic glucocorticoids are mainstay therapies for chronic rhinosinusitis. With respect to local glucocorticoids, nasal spray is used extensively, but some patients do not benefit from short-course treatment.
Zhaofeng Xu   +8 more
doaj   +1 more source

Semi-PBPK Modeling and Simulation to Evaluate the Local and Systemic Pharmacokinetics of OC-01(Varenicline) Nasal Spray

open access: yesFrontiers in Pharmacology, 2022
This study aimed to build a nasal semi-physiologically based pharmacokinetic (PBPK) model to predict the intranasal pharmacokinetic (PK) of the OC-01(varenicline) nasal spray and accelerate the development of this drug.
Xiaofei Wu   +8 more
doaj   +1 more source

Can Sex Improve Nasal Function?—An Exploration of the Link Between Sex and Nasal Function

open access: yesEar, Nose & Throat Journal, 2023
Objectives: This study was conducted to examine the impact of sexual activity on nasal breathing and compare such effect to that of a nasal decongestant.
Olcay Cem Bulut MD   +3 more
doaj   +1 more source

A Randomized, Double-Blinded, Placebo-Controlled, Cross Over Study Evaluating the Efficacy and Safety of Timolol Ophthalmic Solution as an Acute Treatment of Migraine [PDF]

open access: yes, 2020
Introduction. Daily oral beta-adrenoreceptor antagonist has been shown to be effective in preventing migraine headaches. Timolol 0.5% ophthalmic solution is a non-selective beta-adrenoreceptor antago- nist, where the primary use is for glaucoma.
Aggarwal, Dipika   +10 more
core   +2 more sources

Multicentre randomised controlled trial of nasal diamorphine for analgesia in children and teenagers with clinical fractures. [PDF]

open access: yes, 2001
OBJECTIVE: To compare the effectiveness of nasal diamorphine spray with intramuscular morphine for analgesia in children and teenagers with acute pain due to a clinical fracture, and to describe the safety profile of the spray.
Kendall, JM   +3 more
core   +1 more source

Neural correlates of emotion processing comparing antidepressants and exogenous oxytocin in postpartum depressed women: An exploratory study [PDF]

open access: yes, 2019
Despite common use of antidepressants to treat postpartum depression, little is known about the impact of antidepressant use on postpartum brain activity.
Cheng, Hu   +2 more
core   +3 more sources

A nasal spray vaccination device based on Laval nozzle and its experimental test

open access: yesScientific Reports, 2023
In order to realize the application of the nasal spray vaccination in the prevention and protection of respiratory infectious diseases, a nasal spray vaccination device is designed in this paper.
Zhong Wang   +4 more
doaj   +1 more source

Adenosine Triphosphate Bioluminescence Test of the Nasal Spray Nozzles Attached to an Ear-nose-throat Treatment Unit

open access: yesTokyo Women's Medical University Journal, 2018
To report a proper protocol for cleaning and disinfecting the nozzles attached to ear-nose-throat (ENT) treatment unit, contamination of nasal spray nozzle, nasal speculum, and suction tube before and after use was assessed by adenosine triphosphate (ATP)
Yukie YAMAMURA   +3 more
doaj   +1 more source

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