Results 51 to 60 of about 7,581 (224)

A qualitative process evaluation of a nasal spray intervention to prevent respiratory tract infections.

open access: yesPLoS ONE
Nasal sprays could be used to prevent and manage respiratory tract infections (RTIs). As part of a randomized controlled trial (ISRCTN17936080), participants received one of two nasal sprays (gel-based vs. saline) and a digital intervention.
Amelia Dennis   +10 more
doaj   +1 more source

Morpho‐Anatomical and HPTLC Investigations of Lysimachia nummularia L. (Primulaceae) Grown in Switzerland

open access: yesMicroscopy Research and Technique, EarlyView.
This research provides a complete morphoanatomical description of Lysimachia nummularia, as well as a HPTLC profile. Standard techniques of light and scanning electron microscopies, as well as standard techniques of HPTLC, were used. ABSTRACT Primulaceae are distributed all over the world, encompassing around 2590 species.
Carolina Sabedotti   +9 more
wiley   +1 more source

Development of a physiologically relevant method for nasal spray analysis using simulated nasal mucus

open access: yesТонкие химические технологии
Objectives. Current methods for testing nasal spray dosage forms during development fail to fully assess the behavior of the drug following its release from the container, including subsequent distribution, retention, and permeability across the mucosal ...
Yu. M. Domnina   +2 more
doaj   +1 more source

Analytical Challenges and Regulatory Requirements for Nasal Drug Products in Europe and the U.S.

open access: yesPharmaceutics, 2014
Nasal drug delivery can be assessed by a variety of means and regulatory agencies, e.g., the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have published a set of guidelines and regulations proposing in vitro test methods for
Sabrina Trows   +3 more
doaj   +1 more source

Allergic Rhinitis: Updates of Advances

open access: yesB-ENT
Background: In this article, the updates in the advancement of allergic rhinitis (AR) were reviewed. Methods: A search of the literature was performed using PubMed, Medline, Google, and Google Scholar search engines between 1975 and 2024.
Nuray Bayar-Muluk
doaj   +3 more sources

How I Do It: A Novel Case Series of Office‐Based Laser Complete Excision of Vocal Fold Cysts

open access: yesThe Laryngoscope, EarlyView.
Office‐based complete excision of vocal fold cysts using Trublue laser via transnasal flexible endoscopy is a technically feasible alternative to conventional marsupialization, enabling en bloc removal under local anesthesia with excellent procedural tolerability.
Aurora Ka Yue Tam   +5 more
wiley   +1 more source

Comparative study of nasal cavity drug delivery efficiency with different nozzles in a 3D printed model [PDF]

open access: yesPeerJ
Background Nasal sprays are widely used in treating nasal and sinus diseases; however, there are very few studies on the drug delivery efficiency of nasal sprays.
Shengjian Fang   +4 more
doaj   +2 more sources

Transoral Ultrasound in the Diagnostic Workup of Peritonsillar Abscess—A Randomized Clinical Trial

open access: yesThe Laryngoscope, EarlyView.
Peritonsillar abscess frequently mimics peritonsillar cellulitis, exposing many patients to unnecessary and often painful blind needle aspirations. In this multicenter randomized clinical trial of 95 patients, adding transoral ultrasound to standard examination reduced needle aspiration attempts by nearly one third.
Tobias Todsen   +8 more
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

open access: yesThe Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen   +3 more
wiley   +1 more source

Laryngeal Cryotherapy for Neurogenic Cough: Safety, Feasibility, and Prospective Outcomes

open access: yesThe Laryngoscope, EarlyView.
A prospective clinical trial investigated the safety and clinical outcomes of office‐based selective laryngeal cryotherapy for patients with refractory chronic cough. Patient were followed for 6 months posttreatment and had durable improvement in cough severity index and urge‐to‐cough scores and no serious long term adverse effects.
Shumon I. Dhar   +6 more
wiley   +1 more source

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