Results 71 to 80 of about 722,784 (293)
Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy
Human Vaccines & Immunotherapeutics, 2020 The interleukin 6 (IL6) family of proteins regulate important cellular processes and act through a variety of signaling pathways via a shared gp130 receptor.
Anissa A. Widjaja +2 more
doaj +1 more source
Pathophysiology of NASH in endocrine diseases
Endocrine Connections, 2021 Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the industrialized world. NAFLD encompasses a whole spectrum ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) and cirrhosis.
Karim Gariani, François R Jornayvaz
doaj +1 more source
Enabling Stochastic Dynamic Games for Robotic Swarms
Advanced Intelligent Systems, EarlyView.This paper scales stochastic dynamic games to large swarms of robots through selective agent modeling and variable partial belief space planning. We formulate these games using a belief space variant of iterative Linear Quadratic Gaussian (iLQG). We scale to teams of 50 agents through selective modeling based on the estimated influence of agents ...
Kamran Vakil, Alyssa Pierson
wiley +1 more source
Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis
Hepatology, EarlyView., 2022 Diagram of the activation of the profibrotic and procontractile Janus kinase 2 (JAK2)/Ras homolog family member A/Rho‐kinase pathway and the inhibition of phosphorylated JAK2 by pacritinib to inhibit hepatic stellate cell activity. Abstract Background and Aims Janus kinase 2 (JAK2) signaling is increased in human and experimental liver fibrosis with ...
Sandra Torres +21 more
wiley +1 more source
Altered synaptic ultrastructure in the prefrontal cortex of Shank3-deficient rats
Molecular Autism, 2020 Background Deletion or mutations of SHANK3 lead to Phelan–McDermid syndrome and monogenic forms of autism spectrum disorder (ASD). SHANK3 encodes its eponymous scaffolding protein at excitatory glutamatergic synapses.
Sarah Jacot-Descombes +12 more
doaj +1 more source
Scientific Reports, 2023 Major histocompatibility complex class I (MHC-I) proteins are expressed in neurons, where they regulate synaptic plasticity. However, the mechanisms by which MHC-I functions in the CNS remains unknown.
Maciej J. Lazarczyk +11 more
doaj +1 more source
Equilibria Under the Probabilistic Serial Rule [PDF]
, 2015 The probabilistic serial (PS) rule is a prominent randomized rule for assigning indivisible goods to agents. Although it is well known for its good fairness and welfare properties, it is not strategyproof.
Aziz, Haris +5 more
core
Computing all solutions of Nash equilibrium problems with discrete strategy sets
, 2015 The Nash equilibrium problem is a widely used tool to model non-cooperative games. Many solution methods have been proposed in the literature to compute solutions of Nash equilibrium problems with continuous strategy sets, but, besides some specific ...
Sagratella, Simone
core +1 more source
MusicSwarm: Biologically Inspired Intelligence for Music Composition
Advanced Intelligent Systems, EarlyView.Biologically inspired swarms of frozen foundation models self‐organize to compose complex music without fine‐tuning. By coordinating through stigmergic signals, decentralized agents dynamically evolve specialized roles and adapt to solve complex tasks.
Markus J. Buehler
wiley +1 more source
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source