Results 131 to 140 of about 48,656 (208)

USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies

Annals of the New York Academy of Sciences, EarlyView.
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge, Hongying Sun, Jia Zhang, Yang Yang, Jian Mao, Cheliger   +5 more
wiley   +1 more source

Patient‐Centred Web‐Based Information on Head and Neck Squamous Cell Carcinoma: Quality and Readability

Oral Diseases, EarlyView.
ABSTRACT Introduction The internet is a widely used source of health information for patients with head and neck cancer. However, the quality and readability of online content remain inconsistent. This study evaluated the usefulness of web‐based resources by assessing their quality and readability.
Briana Jansen, Stella Mullane, Bryan Tan, Bobby Joseph, Mohammed Junaid, Ramesh Balasubramaniam, Agnieszka Frydrych, Omar Kujan   +7 more
wiley   +1 more source

Correction to “Inhibition of the Numb/Notch Signaling Pathway Increases Radiation Sensitivity in Human Nasopharyngeal Carcinoma Cells”

The Kaohsiung Journal of Medical Sciences, EarlyView.
wiley   +1 more source

Clinicopathologic Analysis of Sarcomas in the Oral and Maxillofacial Region: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to systematically review primary sarcomas in the oral and maxillofacial region, focusing on patient demographics and sarcoma‐specific characteristics, including clinical presentation, histopathology, treatment approaches, outcomes, and survival rates.
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Talita de Carvalho Kimura, Alfio José Tincani, Marcelo Elias Schempf Cattan, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +7 more
wiley   +1 more source

Development and validation of a machine learning-based model for predicting radiation-induced hypothyroidism in nasopharyngeal carcinoma

Radiation Oncology
Background and purpose This study aims to develop a robust and user-friendly prediction model for radiation-induced hypothyroidism (RIHT) in nasopharyngeal carcinoma (NPC) patients. Materials and methods NPC patients treated with IMRT between Jan.
Fangyan Zhong, Wenchao Zhou, Xiying Gao, Dangchi Li, Jianming Zeng, Xiaopeng Xiong, Tianzhu Lu, Xiaochang Gong, Yun Xiao, Jingao Li   +9 more
doaj   +1 more source

Prevalence of mental disorders and their associations with age at diagnosis and time since diagnosis of nasopharyngeal cancer

Frontiers in Public Health
BackgroundDespite advancements in cancer treatment, understanding the long-term mental health implications for nasopharyngeal carcinoma (NPC) survivors remains an underexplored area. This study aims to examine the prevalence of mental disorders and their
Wen-Xuan Wang, Wen-Xuan Wang, Yi-Shan Wu, Yi-Shan Wu, Li-Ping Qi, Li-Ping Qi, Anise M. S. Wu, Anise M. S. Wu, Ying-Ying Zhu, Wei-Jie Gong, Shan-Shan Guo, Shan-Shan Guo, Yi-Jun Hua, Yi-Jun Hua, Dong-Hua Luo, Dong-Hua Luo, Qiu-Yan Chen, Qiu-Yan Chen, Yan-Qun Xiang, Yan-Qun Xiang, Jin-Xin Zhang, Hai-Qiang Mai, Hai-Qiang Mai, Ji-Bin Li, Ji-Bin Li   +24 more
doaj   +1 more source

Construction, expression, and characterization of rSEA-EGF and in vitro evaluation of its antitumor activity against nasopharyngeal cancer [PDF]

, 2018
He, Ying, Liu, Xueting, Tao, Ailin, Wang, Shan, Xie, Yang, Zeng, Liping, Zhang, Jianguo, Zhang, Junyan, Zhou, Zhongqiu, Zou, Zehong   +9 more
core   +2 more sources

Regulation of pyruvate dehydrogenase complex: Dancing to different drums in cancer

International Journal of Cancer, Volume 158, Issue 6, Page 1464-1480, 15 March 2026.
Abstract Mechanisms governing the regulation of pyruvate dehydrogenase complex (PDC) are markedly modified in cancer cells compared to normal cells. PDC activity in normal cells is controlled by the reversible phosphorylation of three serine residues by dedicated kinases and phosphatases.
Mulchand S. Patel, Todd C. Rideout
wiley   +1 more source

Single‐cell transcriptome analysis reveals evolving tumour microenvironment induced by immunochemotherapy in nasopharyngeal carcinoma

Clinical and Translational Medicine
Background Combinatory therapeutic strategy containing immunochemotherapy as part of induction therapy components is one of the current trends in the treatment of high‐risk metastatic locally advanced nasopharyngeal carcinoma (NPC).
Yaofei Jiang, Weixin Bei, Wangzhong Li, Ying Huang, Shuiqing He, Xiaobin Zhu, Lisheng Zheng, Weixiong Xia, Shuhui Dong, Qin Liu, Chuanrun Zhang, Shuhui Lv, Changqing Xie, Yanqun Xiang, Guoying Liu   +14 more
doaj   +1 more source

Biopsy for Suspicious Oral Lesions: A Review From the American Head and Neck Society‐Cancer Prevention Service

Head &Neck, Volume 48, Issue 3, Page 884-892, March 2026.
ABSTRACT Background Oral cancer is often preceded by a precursor lesion. This presents an opportunity for early diagnosis and intervention. Method of biopsy and interpretation are not well standardized and novel methods of analysis are now being investigated.
James Christopher Gates, Heather Edwards, Alessandro Villa, Nick Purdy, Michael Troka, Peter Varela, Quinn Self, Yingci Liu, Yusuf Dundar, Patricia Joyce Brooks, Dauren Adilbay, Andrew Birkeland, John Cramer   +12 more
wiley   +1 more source