Results 171 to 180 of about 1,479,789 (367)

Saucerneol Inhibits the Growth, Migration, and Invasion of Osteosarcoma Cells In Vitro and Prevents Metastasis‐Associated Osteolysis Ex Vivo

open access: yesMolecular Nutrition &Food Research, EarlyView.
Saucerneol (Sauc) is a phytochemical compound classified as a lignan, derived from Saururus chinensis. The JAK2/STAT3 signaling pathway is the primary target of Sauc in osteosarcoma cells. Sauc disrupts mitochondrial potential and increases reactive oxygen species (ROS), leading to apoptotic cell death.
Hyung‐Mun Yun   +3 more
wiley   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

open access: yesVIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma   +6 more
wiley   +1 more source

Novel genetic algorithm‐based individual treatment effect scoring model for optimizing decision‐making: Induction chemotherapy in nasopharyngeal carcinoma

open access: yesVIEW, EarlyView.
To address the limitations of traditional risk‐stratification decision models, this study developed an individualized treatment effect (ITE) scoring model based on a genetic algorithm. By accurately predicting the treatment response to induction chemotherapy and stratifying patients into distinct subgroups, the ITE model holds promise for enhancing ...
Chao Luo   +18 more
wiley   +1 more source

Tumour‐informed workflow to use ctDNA as a biomarker for risk of recurrence in head and neck cancer patients post‐treatment

open access: yesVIEW, EarlyView.
Our study presents a tumour‐informed circulating tumour DNA (ctDNA) workflow designed to enhance the detection of recurrence in head and neck cancer patients, addressing key challenges such as low ctDNA tumour fractions and tumour heterogeneity. Abstract Circulating tumour DNA (ctDNA) is a promising minimally invasive biomarker for monitoring treatment
Xiaomin Huang   +8 more
wiley   +1 more source

Nasopharyngeal carcinoma in greece is associated with elevated levels of EBV-specific antibodies and EBV DNA [PDF]

open access: bronze, 1979
S. I. Koliais   +5 more
openalex   +1 more source

Management of Vocal Fold Leukoplakia

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Vocal fold leukoplakia (VFL) is a descriptive term for a white plaque in the true vocal folds (TVF). It is estimated at 10.2 cases per 100,000 males and 2.1 per 100,000 females. The most critical aspect of managing a VLF is achieving an accurate pathological diagnosis, since a white plaque in the TVF can have numerous differential diagnoses ...
Isabela H. Schettini, Thomas L. Carroll
wiley   +1 more source

Cytopathic effects induced by Epstein-Barr virus replication in epithelial nasopharyngeal carcinoma hybrid cells [PDF]

open access: bronze, 1989
Hiroshi Sato   +5 more
openalex   +1 more source

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