Results 171 to 180 of about 1,451,429 (415)

Classification of Nasopharyngeal Cases using DenseNet Deep Learning Architecture [PDF]

open access: yesarXiv
Nasopharyngeal carcinoma (NPC) is one of the understudied yet deadliest cancers in South East Asia. In Malaysia, the prevalence is identified mainly in Sarawak, among the ethnic of Bidayuh. NPC is often late-diagnosed because it is asymptomatic at the early stage.
arxiv  

Radiation induced lichen planus - an uncommon side effect [PDF]

open access: yes, 2019
Cutaneous lichen planus is classically characterized by violaceous, pruritic, planar papules and plaques, most commonly affecting the extremities. Lichen planus following radiation therapy is extremely rare and lichen planus following radiation therapy ...
Chen, Yi-Chun   +4 more
core  

Random-set methods identify distinct aspects of the enrichment signal in gene-set analysis

open access: yes, 2007
A prespecified set of genes may be enriched, to varying degrees, for genes that have altered expression levels relative to two or more states of a cell.
Ahlquist, Paul   +4 more
core   +1 more source

MicroRNAs as Therapeutic Targets in Nasopharyngeal Carcinoma

open access: yesFrontiers in Oncology, 2019
Nasopharyngeal carcinoma (NPC) is a malignancy of epithelial origin that is prone to local invasion and early distant metastasis. Although concurrent chemotherapy and radiotherapy improves the 5-year survival outcomes, persistent or recurrent disease ...
Sumei Wang, F. Claret, Wanyin Wu
semanticscholar   +1 more source

Safety and Oncologic Outcomes of Endoscopic Endonasal Transcribriform Approach for Locally Advanced Sinonasal Malignancies

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction The past two decades have seen a paradigm shift in the surgical treatment of sinonasal malignancies, moving from traditional open approaches to minimally invasive endoscopic techniques. Technological advancements have enabled the use of the endoscopic endonasal transcribriform approach (EETA) for tumors involving the anterior ...
Michel Khalaf   +11 more
wiley   +1 more source

Universality of a mesenchymal transition signature in invasive solid cancers [PDF]

open access: yes, 2012
In this brief communication, additional computational validation is provided consistent with the unifying hypothesis that a shared biological mechanism of mesenchymal transition, reflected by a precise gene expression signature, may be present in all ...
Dimitris Anastassiou
core   +1 more source

Deep Learning Pipeline for Automated Assessment of Distances Between Tonsillar Tumors and the Internal Carotid Artery

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Evaluating the minimum distance (dTICA) between the internal carotid artery (ICA) and tonsillar tumors (TT) on imaging is essential for preoperative planning; we propose a tool to automatically extract dTICA. Methods CT scans of 96 patients with TT were selected from the cancer imaging archive.
Aseem Jain   +4 more
wiley   +1 more source

Identifying optimal candidates for local treatment of the primary tumor among patients with de novo metastatic nasopharyngeal carcinoma: a retrospective cohort study based on Epstein–Barr virus DNA level and tumor response to palliative chemotherapy

open access: yesBMC Cancer, 2019
Background To evaluate the clinical outcome in patients with de novo metastatic nasopharyngeal carcinoma (NPC) treated or not treated with locoregional radiotherapy (LRRT) based on plasma Epstein–Barr virus (EBV) DNA level and tumor response after ...
Xue-Song Sun   +13 more
doaj   +1 more source

Leveraging Semantic Asymmetry for Precise Gross Tumor Volume Segmentation of Nasopharyngeal Carcinoma in Planning CT [PDF]

open access: yesarXiv
In the radiation therapy of nasopharyngeal carcinoma (NPC), clinicians typically delineate the gross tumor volume (GTV) using non-contrast planning computed tomography to ensure accurate radiation dose delivery. However, the low contrast between tumors and adjacent normal tissues necessitates that radiation oncologists manually delineate the tumors ...
arxiv  

Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression

open access: yesOncoTargets and Therapy, 2019
Objective: Shikonin has inhibitory effects against nasopharyngeal carcinoma that are mediated through the apoptotic pathway. However, necroptosis signaling pathways may enable the elimination of apoptosis-resistant cancers when induced with targeted ...
Tiancong Liu, Xun Sun, Z. Cao
semanticscholar   +1 more source

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