Results 171 to 180 of about 48,656 (208)

Single‐Port Transoral Robotic Surgery for Head and Neck Lesions and Obstructive Sleep Apnea: A Prospective Real‐World Case Series From Taiwan

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 1, February 2026.
Setup of the da Vinci SP system. (A) The SP port is positioned transorally with the robotic cart docked at the patient’s head. (B) Two or three instruments and a 3D endoscope are inserted via a single port. ABSTRACT Objectives To assess the clinical practicality, procedural characteristics, and short‐term recovery outcomes of single‐port transoral ...
Ting‐Shen Lin   +5 more
wiley   +1 more source

Malignant Otitis Externa Presenting With Nasopharyngeal Hematoma: A Case Report of an Unusual Complication

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 1, February 2026.
ABSTRACT Objective Malignant otitis externa (MOE) is a potentially life‐threatening infection of the external auditory canal (EAC), often with skull base extension. Vascular complications are exceptionally rare, with only six reports of petrous internal carotid artery (ICA) pseudoaneurysm following MOE.
Vanessa Hui En Chen   +2 more
wiley   +1 more source

Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications

open access: yesMedComm, Volume 7, Issue 2, February 2026.
The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin   +12 more
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian   +8 more
wiley   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

open access: yesMedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang   +10 more
wiley   +1 more source

State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding   +6 more
wiley   +1 more source

Facial reconstruction with implants of porous polyethylene [PDF]

open access: yes, 1985
Berghaus, Alexander, Myers, Eugene N.
core  

Auditory Preservation in Nasopharyngeal Carcinoma: Comparison of Proton and Photon Radiotherapy

open access: yesOtolaryngology–Head and Neck Surgery, Volume 174, Issue 2, Page 450-457, February 2026.
Abstract Objective To compare cochlear dose and hearing outcomes between intensity‐modulated proton therapy (IMPT) and volumetric modulated arc therapy (VMAT) in patients with nasopharyngeal carcinoma (NPC). Study Design Prospective matched cohorts. Setting Tertiary academic center.
Kuang‐Hsu Lien   +11 more
wiley   +1 more source

Insulin‐Like Growth Factor 1 Receptor Expression for Predicting PD‑1/PD‑L1 Inhibitor Response in Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 112-123, February 2026.
ABSTRACT Objectives Insulin‐like growth factor 1 receptor (IGF‐1R) is crucial for immunological control and the development of different types of cancer. It is still uncertain how the expression of IGF‐1R impacts hypopharyngeal squamous cell carcinoma (HPSCC) and whether it has any predictive value for prognosis.
Wen‐Jing Li   +10 more
wiley   +1 more source

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