Results 61 to 70 of about 61,475 (266)

Concurrent chemoradiotherapy plus nimotuzumab versus chemoradiotherapy alone for locoregionally advanced nasopharyngeal carcinoma with a suboptimal response to induction chemotherapy: a randomized phase 2 trial

Nature Communications
Induction chemotherapy (IC) followed by concurrent chemoradiotherapy (CCRT) is the standard treatment for locoregionally advanced nasopharyngeal carcinoma (LA-NPC); however, patients with a suboptimal response to IC, defined as detectable Epstein–Barr ...
Li-Ting Liu, Xue-Song Sun, Ting-Ting Quan, Xiao-Yun Li, Ling Guo, Hao-Yuan Mo, Shan-Shan Guo, Sai-Lan Liu, Ying Huang, Dong-Hua Luo, Rui Sun, Guo-Dong Jia, Ji-Bin Li, Qing Liu, Pan Wang, Yu-Jing Liang, Jie Chen, Yi-Fu Li, Hui Cheng, Wei-Xiong Xia, Fang Qiu, Jin-Hao Yang, Qi Yang, Dong-Xiang Wen, Jin-Jie Yan, Chong Zhao, Qiu-Yan Chen, Lin-Quan Tang, Hai-Qiang Mai   +28 more
doaj   +1 more source

Incidence and Site‐Specific Risk Factors of Jaw Osteoradionecrosis for Head and Neck Patients in the IMRT/VMAT Era: Evidence From a Large, Hospital‐Based Cohort

Head &Neck, EarlyView.
ABSTRACT Purpose Osteoradionecrosis (ORN) of the jaw remains a serious late complication of head and neck cancer (HNC) radiotherapy. Although intensity‐modulated radiotherapy (IMRT) and volumetric‐modulated arc radiotherapy (VMAT) are expected to reduce ORN risk, large real‐world data in the modern era are limited.
Fang‐Yu Wu, Hui‐Hsin Ko, Hsiang‐Fong Kao, Shih‐Jung Cheng   +3 more
wiley   +1 more source

Nasopharyngeal carcinoma detected noninvasively in the real world using three gene methylation analyses from automatically processed bilateral nasal swab samples

BMC Cancer
Background Efforts have been made to improve the performance of nasopharyngeal carcinoma screening strategies, which include EBV related biomarkers. However, the advances achieved still remain imperfection.
Zi-Han Qin, Si-Yuan Chen, Shuai Zhou, Hua Deng, Lan-Xi Li, Qi-Lun Guo, Xiong Zou, Pei-Yu Huang, Ming-Yuan Chen, Liang Zhang, Yi-Jun Hua   +10 more
doaj   +1 more source

RETRACTION: LncRNA AATBC Regulates Pinin to Promote Metastasis in Nasopharyngeal Carcinoma

Molecular Oncology, EarlyView.
RETRACTION: T. Tang, L. Yang, Y. Cao, M. Wang, S. Zhang, Z. Gong, F. Xiong, Y. He, Y. Zhou, Q. Liao, B. Xiang, M. Zhou, C. Guo, X. Li, Y. Li, W. Xiong, G. Li, and Z. Zeng, “LncRNA AATBC Regulates Pinin to Promote Metastasis in Nasopharyngeal Carcinoma,” Molecular Oncology 14, no. 9 (2020): 2251‐2270, https://doi.org/10.1002/1878‐0261.12703.
wiley   +1 more source

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

Head &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun, Seyoung Seo, Jang Ho Cho, Keon‐Uk Park, Sang‐Cheol Lee, Yong Won Choi, Tak Yun, Seong Hoon Shin, Sung‐Bae Kim, Seungeun Lee, Chang Ho Ahn, Bhumsuk Keam   +11 more
wiley   +1 more source

Comparison of long-term quality of life and their predictors in survivors between paediatric and adult nasopharyngeal carcinoma in the intensity-modulated radiotherapy era

BMC Cancer
Background To compare the differences in long-term quality of life (QoL) between survivors of paediatric and adult patients with nasopharyngeal carcinoma (NPC) and assess the clinical factors that predict long-term QoL.
Jing Jin, Shan-Shan Guo, Li-Ting Liu, Dong-Xiang Wen, Rong-Ping Liu, Jie-Yi Lin, Si-Qi Liu, Xue-Song Sun, Yu-Jing Liang, Lin-Quan Tang, Hai-Qiang Mai, Qiu-Yan Chen   +11 more
doaj   +1 more source

The Role of Multicancer Early Detection Tests in Head and Neck Squamous Cell Carcinoma: A Case Series

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) lacks an established screening program, and most cases are diagnosed at advanced stages. Multi‐cancer early detection (MCED) blood‐based assays represent a promising approach, yet real‐world clinical experience with MCED‐identified HNSCC remains limited.
Abhinav Talwar, Olivia Ben‐Levy, Nikhil Sriram, Sandeep Samant   +3 more
wiley   +1 more source

Measurement Tools for Radiation‐Induced Fibrosis in Head and Neck Cancer: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Radiation‐induced fibrosis is a common, often debilitating late effect of head and neck cancer (HNC) treatment. An updated systematic review is needed to evaluate the reliability, validity, and clinical utility of fibrosis measurement tools.
Vanessa Helou, Pooja D. Reddy, Purva H. Rumde, Mary L. Klem, Sagar G. Kansara, Oldrich Virag, Yvonne M. Mowery, Nicole N. Scheff, Matthew E. Spector, Shaum Sridharan, Marci L. Nilsen, Kevin J. Contrera   +11 more
wiley   +1 more source

Whether Primary Bone‐Only Oligometastatic Nasopharyngeal Carcinoma Patients Benefit From Radiotherapy to the Bones on the Basis of Palliative Chemotherapy Plus Locoregional Radiotherapy?—A Large‐Cohort Retrospective Study

Cancer Medicine
Objectives Whether to perform local radiotherapy on metastatic bone for primary bone‐only oligometastatic nasopharyngeal carcinoma (NPC) patients remains unclear.
Wan‐Ping Guo, Guo‐Dong Jia, Si‐Yi Xie, Xuan Yu, Xiao‐Han Meng, Lin‐Quan Tang, Xiao‐Yun Li, Dong‐Hua Luo   +7 more
doaj   +1 more source

Imaging of Nasopharyngeal Carcinoma

Annals of the Academy of Medicine, Singapore, 2009
Nasopharyngeal cancer (NPC) is a unique disease that shows clinical behaviour, epidemiology and histopathology that is different from that of other squamous cell carcinomas of the head and neck. Magnetic resonance imaging (MRI) is now the preferred imaging modality in the assessment and staging of NPC, especially in relation to its superior soft tissue
Julian, Goh, Keith, Lim
openaire   +2 more sources