Results 91 to 100 of about 386,285 (319)
Abstract Objective Coronavirus disease‐19 (COVID‐19), caused by SARS‐CoV‐2, has led to a global pandemic since December 2019. People with epilepsy (PwE) face higher risks of severe COVID‐19 outcomes and may be more vulnerable to long‐term neurological and psychiatric effects. Methods This multicenter, retrospective cohort study reviewed medical records
Fedele Dono+8 more
wiley +1 more source
Single‐Cell Transcriptomic Analysis of the Immune Response to COVID‐19 and Tuberculosis Coinfection
Understanding the immunological basis for severe outcomes in COVID‐19/Tuberculosis coinfection is critical. Our single‐cell analysis identifies key drivers: profound lymphocyte loss through combined apoptosis and altered trafficking, excessive S100 protein‐mediated inflammation contributing to cytokine storms, and systemic immune dysfunction ...
Yi Wang+20 more
wiley +1 more source
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu+5 more
wiley +1 more source
ABSTRACT Background Head and neck cancer (HNC) significantly impacts older adults, with mortality influenced by multiple factors. The Multidimensional Prognostic Index (MPI), derived from comprehensive geriatric assessment (CGA), may improve risk stratification and clinical decision making. Methods An observational cohort study was conducted at Erasmus
Ajay T. Bakas+5 more
wiley +1 more source
ABSTRACT Background Evaluating the minimum distance (dTICA) between the internal carotid artery (ICA) and tonsillar tumors (TT) on imaging is essential for preoperative planning; we propose a tool to automatically extract dTICA. Methods CT scans of 96 patients with TT were selected from the cancer imaging archive.
Aseem Jain+4 more
wiley +1 more source
ABSTRACT Background Head and neck cancer patients often present with locally advanced disease. For some patients, palliative treatment schedules focused on symptom control are often preferred. Perhaps the most widely used of these is the so‐called Quad Shot (QS) regimen.
Eirini Nikolaidou+5 more
wiley +1 more source
Randomized Controlled Trial Comparing Virgin Coconut Oil and Salt and Soda Mouthwash Versus Salt and Soda Mouthwash Alone in Preventing Grade 2 and Above Radiation-Induced Mucositis in Patients With Nasopharyngeal Neoplasm (VCO-PRIM STUDY) [PDF]
M.C. Cruz
openalex +1 more source
Geographic and Socioeconomic Landscape of Veterans With Head and Neck Cancer
ABSTRACT Background US Veterans experience higher rates and worse outcomes for head and neck squamous cell carcinoma (HNSCC) compared to civilians. Geographic and socioeconomic barriers remain unclear. Methods This retrospective descriptive study analyzed VA data nationwide (2012–2022), identifying Veterans with HNSCC using ICD codes. Subsites included
Kristen L. Zayan+8 more
wiley +1 more source
Central nervous system changes complicating the use of radiotherapy for the treatment of a nasopharyngeal neoplasm in a diabetic patient [PDF]
Bruce A. Smith+3 more
openalex +1 more source
The Management of Head and Neck Lymphoedema: A 2025 Systematic Review
ABSTRACT Background Head and Neck Lymphoedema (HNL) is debilitating to many domains of patients' structure and function, yet it is the most poorly researched form of lymphoedema. This is due to the variety of signs and symptoms experienced by HNL patients, and this makes it difficult to formulate standardized staging classifications and treatment ...
Rohan Rajaram+4 more
wiley +1 more source