Results 111 to 120 of about 53,403 (325)

معرفی يک مورد بيمار مبتلا به کارسينوم نورواندوکرين نازوفارنکس [PDF]

, 2007
مقدمه: کارسينوم نورواندوکرين از جمله نئوپلاسم‌های سيستم نورواندوکرين می‌باشد که مشتمل بر ارگان‌هايی است که سلولهای APUD(Amine precursor uptake & decarboxylation) در آنها ناشايعند. در بدن انسان، شايع‌ترين محل کارسينوم، دستگاه GI(Gastrointestinal) و ريه می‌
امامی, سید علیرضا, محبی, علیرضا   +1 more
core  

Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects [PDF]

, 2007
Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection.
Braun, Gerald S., Horster, Sophia, Ihrler, Stephan, Schmid, Holger, Wagner, Katrin S.   +4 more
core   +2 more sources

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Development of a luciferase/luciferin cell proliferation (XenoLuc) assay for real-time measurements of Gfp-Luc2-modified cells in a co-culture system

BMC Biotechnology, 2019
Background In vitro modelling of cancer cells is becoming more complex due to prevailing evidence of intimate interactions between cancer cells and their surrounding stroma. A co-culture system which consists of more than one cell type is physiologically
Sin-Yeang Teow, Kitson Liew, Mohd Firdaus Che Mat, Marini Marzuki, Norazlin Abdul Aziz, Tai-Lin Chu, Munirah Ahmad, Alan Soo-Beng Khoo   +7 more
doaj   +1 more source

Interleukin-4 and interferon- γ levels in Epstein-Barr virus-associated infectious mononucleosis and nasopharyngeal carcinoma [PDF]

, 2011
Background: Cytokines have been suggested to participate in the pathogenesis of infectious mononucleosis (IM) and nasopharyngeal carcinoma (NPC). METHODS: Serum levels and gene expression of interleukin-4 (IL-4) and interferon-γ (IFN-γ) were assessed
Budiani, Dyah R., Haryana, Sofia M., Sosroseno, Wihaskoro   +2 more
core   +1 more source

Enhancement of radiosensitivity by the novel anticancer quinolone derivative vosaroxin in preclinical glioblastoma models [PDF]

, 2017
Purpose: Glioblastoma multiforme (GBM) is the most aggressive brain tumor. The activity of vosaroxin, a first-in-class anticancer quinolone derivative that intercalates DNA and inhibits topoisomerase II, was investigated in GBM preclinical models as a ...
Colapietro, Alessandro, Di Cesare, Ernesto, Festuccia, Claudio, Fox, Judith A., Gravina, Giovanni Luca, Mancini, Andrea, Marampon, Francesco, Mattei, Claudia, Rossi, Giulia, Ventura, Luca, Vetuschi, Antonella, Vitale, Flora   +11 more
core   +1 more source

GERD and Upper Aerodigestive Tract Cancer Risk: A Systematic Review and Meta‐Analysis

The Laryngoscope, EarlyView.
ABSTRACT Objective Gastroesophageal reflux disease (GERD) is highly prevalent, yet its association with upper aerodigestive tract (UADT) cancers beyond esophageal adenocarcinoma remains incompletely defined. This systematic review and meta‐analysis aimed to quantify the risk of specific UADT cancers in individuals with GERD.
Janice Huang, Nicolas Jo, Garret Forman, Tonya Aaron, Sophia Peifer, Soumil Prasad, Luke van Leeuwen, Laura Wild, Nicholas DiStefano, Zhibin Chen, Elizabeth Franzmann   +10 more
wiley   +1 more source

Nasopharyngeal carcinoma: presenting symptoms and duration before diagnosis [PDF]

, 1997
This is a retrospective analysis of 4768 patients with undifferentiated or non-keratinising carcinoma of the nasopharynx who were treated during 1 January 1976 to 31 December 1985.
Foo, W, Lau, WH, Law, SC, Lee, WMA, O, SK, Poon, YF, Sze, WM, Tung, SY   +7 more
core  

Unilateral Nasopharyngeal Endoscopic Resection Type III: Technical Notes 

The Laryngoscope, EarlyView.
The present video case report details technical notes of Nasopharyngeal Endoscopic Resection (NER) Type III, performed for a mucosal melanoma in a 71‐year‐old patient. Key surgical steps—such as achieving optimal exposure, employing Doppler‐guided internal carotid artery localization, and applying vascularized flap coverage—are outlined, demonstrating ...
Carlo Conti, Gabriele Testa, Davide Mattavelli, Vittorio Rampinelli, Claudia Lodovica Modesti, Aurora Pinacoli, Alberto Schreiber, Cesare Piazza   +7 more
wiley   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source