Results 61 to 70 of about 51,742 (351)

Nasopharyngeal masses in adults—A retrospective analysis of 255 patients to evaluate symptoms, clinical findings, and histological results

open access: yesWorld Journal of Otorhinolaryngology-Head and Neck Surgery
Background Nasopharyngeal tissue hyperplasia is generally associated with adenoids in childhood. In adults, nasopharyngeal masses are occasionally found, but data on symptoms, clinical findings, and histologic results are limited.
Melanie M. vonWitzleben   +3 more
doaj   +1 more source

NamiRNA‐Enhancer Network: The Changing Era Challenge and Chance of miRNA

open access: yesAdvanced Science, EarlyView.
MiRNAs (miRNAs) regulate diverse biological processes across species. Unlike canonical miRNA‐mediated gene repression, Nuclear Activating miRNAs (NamiRNAs) can efficiently upregulate gene expression by targeting enhancers. This review systematically summarizes recent advances in NamiRNA research, elucidates the theory of NamiRNA‐Enhancer‐mediated Gene ...
Lu Chen   +13 more
wiley   +1 more source

Diffusion-weighted Magnetic Resonance Imaging Evaluates Salivary Gland Function Damage in Nasopharyngeal Carcinoma Patients Treated with Intensity-modulated Radiation Therapy

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To evaluate salivary gland function damage and analyze related factors by diffusion-weighted magnetic resonance imaging (DW-MRI) in patients with nasopharyngeal carcinoma after intensity modulated radiation therapy.
LIU Guichao   +6 more
doaj   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Head and Neck Cancer Trends in Semarang: An analysis of ASR and ASCR [PDF]

open access: yes, 2015
Background: The sustainable incidence data of Head and Neck Cancer is poorly described in Indonesia. There was no large-scale epidemiological study of head and neck cancer in Indonesia, especially in Semarang and surrounding areas.
Hidanti, Mazaya Luthfia, PRASETYO, AWAL
core   +1 more source

Engineering Bacteria as Living Therapeutics in Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Through synthetic biology approaches, natural bacteria can be genetically programmed into multifunctional living therapeutics. These engineered bacteria are capable of secreting anti‐tumor factors, displaying tumor‐associated antigens on their surface, or undergoing programmed self‐lysis to release therapeutic cargo.
Jiangfeng Chen   +6 more
wiley   +1 more source

Mature Nasopharyngeal Teratoma in a Child

open access: yesCase Reports in Otolaryngology, 2015
Teratomas are neoplasms derived from the germ cell with components of all the three embryonic layers. These are rare neoplasms in head and neck region which can occur in any age group but are more prevalent in children. The present case is an 11-year-old
Ramesh Parajuli   +2 more
doaj   +1 more source

Clathrin Light Chain B Drives Hepatocellular Carcinoma Progression Through Dual Mechanisms: Small Extracellular Vesicle‐Mediated Angiogenesis and the NF‐κB–PCLAF Signaling Axis

open access: yesAdvanced Science, EarlyView.
Clathrin Light Chain B (CLTB) drives hepatocellular carcinoma progression through dual pathways: intracellularly, it activates the NF‐κB–PCLAF axis to enhance small extracellular vesicle (sEV) uptake and tumor proliferation; extracellularly, CLTB‐enriched sEVs bind SH3KBP1 to inhibit its degradation, inducing angiogenesis and vascular leakage ...
Xiaoke Sun   +7 more
wiley   +1 more source

Toripalimab: the First Domestic Anti-Tumor PD-1 Antibody in China

open access: yesFrontiers in Immunology, 2022
Toripalimab (Tuoyi™) is a selective, recombinant, humanized monoclonal antibody against programmed death protein 1 (PD-1) developed by Shanghai Junshi Bioscience Co., Ltd.
Lin Zhang   +3 more
doaj   +1 more source

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