Results 71 to 80 of about 386,285 (319)

Development of neoplasms in pediatric patients with rheumatic disease exposed to anti-tumor necrosis factor therapies: a single Centre retrospective study

Pediatric Rheumatology Online Journal, 2018
Background Anti-TNF (Tumor necrosis factor) therapy is effective in treating pediatric patients with refractory rheumatic disease. There is however a concern that anti-TNF usage may increase the risk of malignancy. Reports on specific types of malignancy
Alexandra Okihiro, Rachana Hasija, Lillia Fung, Bonnie Cameron, Brian M. Feldman, Ronald Laxer, Rayfel Schneider, Earl Silverman, Lynn Spiegel, Rae S. M. Yeung, Shirley M. L. Tse   +10 more
doaj   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Hearing Loss and Middle Ear Effusion in Nasopharyngeal Carcinoma Following Radiotherapy: Dose–Response Relationship and Normal Tissue Complication Probability Modeling

International Archives of Otorhinolaryngology
Introduction Radiotherapy is the primary treatment for nasopharyngeal carcinoma. Radiation exposure to the cochlea and middle ear can cause hearing loss.
Prem Wungcharoen, Anussara Prayongrat, Napadon Tangjaturonrasme   +2 more
doaj   +1 more source

The Links between Parkinson’s Disease and Cancer

Biomedicines, 2020
Epidemiologic studies indicate a decreased incidence of most cancer types in Parkinson’s disease (PD) patients. However, some neoplasms are associated with a higher risk of occurrence in PD patients. Both pathologies share some common biological pathways.
Maria Ejma, Natalia Madetko, Anna Brzecka, Konstanty Guranski, Piotr Alster, Marta Misiuk-Hojło, Siva G. Somasundaram, Cecil E. Kirkland, Gjumrakch Aliev   +8 more
doaj   +1 more source

Enhancing Spinal Metastasis Detection and Feature Evaluation on Computed Tomography Scans Using Deep‐Learning Systems

Advanced Intelligent Systems, EarlyView.
A deep‐learning system (DLS) is developed for the automatic detection of spinal metastases and the evaluation of associated features using computed tomography imaging. A multireader, multicase analysis and a prospective multicenter cohort study are conducted to evaluate the diagnostic performance.
Zhiyu Wang, Guangyu Yao, Shengyuan Xu, Yifeng Gu, Yujie Chang, Jing Sun, Jingyi Guo, Shiqi Peng, Bolin Lai, Xiaoyun Zhang, Chunbin Wang, Haiying Jiang, Surong Chen, Yanfeng Wang, Ya Zhang, Yuehua Li, Hui Zhao   +16 more
wiley   +1 more source

Epstein-barr virus induced cellular changes in nasal mucosa

Virology Journal, 2006
A 21-year-old man presented with nasal obstruction of the right nasal fossa of 1 year duration. Nasal endoscopy revealed in the right inferior turbinate head a rounded neoplasm about 1 cm in diameter.
Calvario Agata, Fiorella Maria, Besozzi Gaspare, Cassano Michele, Tomaiuolo Marilena, Gelardi Matteo, Castellano Maria, Cassano Pasquale   +7 more
doaj   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Nasopharyngeal Mantle Cell Lymphoma: An Extremely Rare Entity

Oman Medical Journal, 2019
Mantle cell lymphoma (MCL) is a rare, aggressive subtype of non-Hodgkin lymphoma with a poor prognosis and high recurrence rate. It seldom affects the Waldeyer’s ring let alone the nasopharynx.
Mark Paul, Najihah Hanim Asmi, Eshamsol Kamar Omar, Suhaila Abdullah, Irfan Mohamad   +4 more
doaj   +1 more source

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source