Results 81 to 90 of about 51,742 (351)

Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent Apoptosis, but are insensitive to direct activation with exogenous fas ligand [PDF]

, 2010
Introduction Cholangiocarcinoma is a rare malignancy of the biliary tract, the incidence of which is rising, but the pathogenesis of which remains uncertain.
A Bergamo, A Eliopoulos, A Ottaiano, A Pickens, AB Alexandroff, AH Klimp, AJ Baxendale, AM Cleary, AR Hayward, B Ansari, C Esche, D Wang, David H. Adams, DG Wingett, E Alabraba, E Bonfoco, E Jakobsen, Elizabeth H. Humphreys, F Mach, FG Que, G Pan, H Dzojic, H Le-Niculescu, HD Ochs, HR Shin, I Cascino, I Stamenkovic, J Ahmed-Choudhury, JL Ferrant, JR Maxwell, K Harada, Kevin T. Williams, KT Williams, LE French, M Fan, MC Rissoan, Mikhail V. Blagosklonny, MV Clement, N Itoh, P Angel, P Chu, P Starkel, P Watanapa, PA Lipsett, R Joplin, R Stewart, RH Vonderheide, RJ Armitage, RS Chapman, S Hess, S Kubo, S Paulie, SA Khan, SC Afford, SC Afford, SC Afford, SC Afford, Simon C. Afford, SM Abmayr, T Ohtsuka, T Shimonishi, T Suda, U Broome, U Bugajska, U Gaur, U Schonbeck, W Schuler, YS Zong   +67 more
core   +3 more sources

Lactylation in cancer biology: Unlocking new avenues for research and therapy

Cancer Communications, EarlyView.
Abstract Lactylation, a newly identified post‐translational modification, plays a multifaceted role in cancer biology by integrating epigenetic and non‐epigenetic mechanisms. This review summarizes the latest research progress on lactylation, including its functions in epigenetic regulation and its broader impact on cellular processes.
Xiaoyu Hou, Zhenya Hong, Huimin Zeng, Changyi Zhang, Peng Zhang, Ding Ma, Zhiqiang Han   +6 more
wiley   +1 more source

Experiencia en el tratamiento quirúrgico del angiofibroma nasal juvenil en Hospital de Especialidades No 2 Lic. Luis Donaldo Colosio Murrieta. Instituto Mexicano del Seguro Social de Ciudad Obregón, Sonora

Horizonte Médico, 2018
Objective: To present our experience and assess the recurrence of juvenile nasopharyngeal angiofibroma after a surgical treatment (open versus endoscopic approach) in the country’s northwestern Department of Otorhinolaryngology.
Rubio-Espinoza A, Lugo-Machado J.A, Méndez-Cázares J.A, González-Quintana J.E, Portillo-Flores J.A   +4 more
doaj   +1 more source

The Links between Parkinson’s Disease and Cancer

Biomedicines, 2020
Epidemiologic studies indicate a decreased incidence of most cancer types in Parkinson’s disease (PD) patients. However, some neoplasms are associated with a higher risk of occurrence in PD patients. Both pathologies share some common biological pathways.
Maria Ejma, Natalia Madetko, Anna Brzecka, Konstanty Guranski, Piotr Alster, Marta Misiuk-Hojło, Siva G. Somasundaram, Cecil E. Kirkland, Gjumrakch Aliev   +8 more
doaj   +1 more source

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, EarlyView.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Utility of magnetic resonance imaging in determining treatment response and local recurrence in nasopharyngeal carcinoma treated curatively

BMC Cancer, 2020
Background To determine the optimal timing of the first Magnetic Resonance Imaging (MRI) scan after curative-intent radiotherapy (RT) for nasopharyngeal carcinoma (NPC), and evaluate the role of MRI in surveillance for locoregional recurrence (LRR ...
Katherine Meng, Jeremy Tey, Francis Cho Hao Ho, Hira Asim, Timothy Cheo   +4 more
doaj   +1 more source

Proptosis due to otolaryngology causes a study [PDF]

, 2013
Proximity of orbit to nose and paranasal sinuses makes it rather vulnerable to insults due to otolaryngological causes. The medial wall of orbit (Lamina papyracea) is rather paper thin and ithappens to form the lateral wall of anterior ethmoid air cells.
Kothandaraman, Kamakshi, Thiagarajan, Balasubramanian   +1 more
core   +1 more source

Vinpocetine Overcomes Paclitaxel Resistance in a Triple‐Negative Breast Cancer Cell Line

Cell Biology International, EarlyView.
ABSTRACT Paclitaxel is a first‐line treatment for triple‐negative breast cancer (TNBC), but its efficacy is commonly limited by tumor‐cell resistance. Vinpocetine is a well‐tolerated dietary supplement with pleiotropic cellular effects, including potential anti‐tumor activity.
Hsiao‐Hui Kuo, Chien‐Wei Huang, Wei‐Rou Chiang, Ling‐Huei Yih   +3 more
wiley   +1 more source

Juvenile Nasopharyngeal Angiofibroma: A Series of 96 Surgical Cases

International Archives of Otorhinolaryngology
Introduction Juvenile nasopharyngeal angiofibroma (JNA) is a benign vascularized tumor that affects almost exclusively male adolescents. Surgery is the treatment of choice for JNA.
Alexandre Wady Debes Felippu, Erica Batista Fontes, André Wady Debes Felippu, Bruna Coelho Ellery, Ana Carolina Silveira de Oliveira, André Vicente Guimarães, Filippo Cascio, Alexandre Felippu   +7 more
doaj   +1 more source

Epstein-barr virus induced cellular changes in nasal mucosa

Virology Journal, 2006
A 21-year-old man presented with nasal obstruction of the right nasal fossa of 1 year duration. Nasal endoscopy revealed in the right inferior turbinate head a rounded neoplasm about 1 cm in diameter.
Calvario Agata, Fiorella Maria, Besozzi Gaspare, Cassano Michele, Tomaiuolo Marilena, Gelardi Matteo, Castellano Maria, Cassano Pasquale   +7 more
doaj   +1 more source