Results 111 to 120 of about 23,350,035 (239)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Implementation of the Strengthening Community Organisations Action Plan [PDF]
, 2013 Community organisations are a significant provider of services, including health, education, aged care, social services, and sport and recreational activities.
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Utility Best Practices Guidance for Providing Business Customers with Energy Use and Cost Data [PDF]
, 2008 This publication is the major findings on activity of the National Action Plan for Energy Efficiency.
National Action Plan for Energy Efficiency
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Embu County Climate Change Action Plan 2023-2027 [PDF]
The Embu County Climate Change Action Plan (ECCCAP) for the period 2023-2027 aims to enable Embu County to take significant steps to combat the effects of climate change and enhance the resilience of Embu County's communities and residents.
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Affirmative Action Plan, 1999-2000 [PDF]
, 1999 Illinois State University Affirmative Action Planhttps://ir.library.illinoisstate.edu/affirmative-action-reports/1009/thumbnail ...
Affirmative Action Plan 1999-00 Working Team,
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Department of Economics Action Plan
, 2013 Department of Economics Action Plan for Academic Program ReviewDepartment of Economics, Action Plan, Academic Program ReviewDepartment of Economics, Action Plan, Academic Program ...
Economics +2 more
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