Results 31 to 40 of about 373,386 (221)

The Association between Fatalistic Beliefs and Late Stage at Diagnosis of Lung and Colorectal Cancer. [PDF]

, 2015
BACKGROUND: Fatalistic beliefs may be implicated in longer help-seeking intervals, and consequently, greater risk of advanced stage at cancer diagnosis.
Abel, Gary A, Keating, Nancy L, Liu, Michael Pang-Hsiang, Lyratzopoulos, Georgios, Wardle, Jane   +4 more
core   +2 more sources

JAK2/IDH-mutant–driven myeloproliferative neoplasm is sensitive to combined targeted inhibition [PDF]

, 2018
Patients with myeloproliferative neoplasms (MPNs) frequently progress to bone marrow failure or acute myeloid leukemia (AML), and mutations in epigenetic regulators such as the metabolic enzyme isocitrate dehydrogenase (IDH) are associated with poor ...
Alan H. Shih, Allison N. Lau, Amritha Varshini Hanasoge Somasundara, Andrew M. Intlekofer, Anna Sophia McKenney, April Chiu, Barbara Spitzer, Craig B. Thompson, Efthymia Papalexi, Elizaveta Freinkman, Esra A. Akbay, Franck T. Rapaport, Gaujoux, Jihae Ahn, Julie Teruya-Feldstein, Kaitlyn Shank, Katharine Yen, Kwok-Kin Wong, Matthew G. Vander Heiden, Mesa, Minal A. Patel, Mya Steadman, Raajit Rampal, Raj Nagaraja, Ross L. Levine, Stein, Tefferi   +26 more
core   +1 more source

Por que as Pesquisas em Oncologia Integrativa são Importantes?

Revista Brasileira de Cancerologia, 2013
A Oncologia Integrativa (OI), termo cunhado por Dr. Robert Wittes, diretor da unidade de tratamento e diagnóstico do câncer do National Cancer Institute (NCI), em 2000, é um ramo da Medicina Integrativa que usa práticas alternativas e complementares ...
Pamela Siegel, Nelson Filice de Barros
doaj   +1 more source

Inhibitor of DNA binding proteins revealed as orchestrators of steady state, stress and malignant hematopoiesis

Frontiers in Immunology, 2022
Adult mammalian hematopoiesis is a dynamic cellular process that provides a continuous supply of myeloid, lymphoid, erythroid/megakaryocyte cells for host survival.
Shweta Singh, Tanmoy Sarkar, Brad Jakubison, Brad Jakubison, Stephen Gadomski, Andrew Spradlin, Kristbjorn O. Gudmundsson, Kristbjorn O. Gudmundsson, Jonathan R. Keller, Jonathan R. Keller   +9 more
doaj   +1 more source

The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy. [PDF]

, 2011
BackgroundTumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates. Tumor microenvironments, however, are difficult to study in vitro.
Broaddus, V Courtney, Feng, Mingqian, Fitzgerald, David, Hassan, Raffit, Ho, Mitchell, Nagashima, Kunio, Phung, Yen, Xiang, Xinran, Zhang, Jingli   +8 more
core   +3 more sources

Impact of COVID-19 Pandemic on Medical Practices

Asian Pacific Journal of Cancer Care, 2022
The COVID-19 pandemic has affected human life in all spheres. However, the medical and health practices seen changed a lot since the arrival of this pandemic. This article describes the positive and negative impact of covid in the medical field.
Balbir Kumar, Rakesh Garg, Prashant Sirohyia, Brajesh Kumar Ratre, Ram Singh   +4 more
doaj   +1 more source

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression

Molecular Systems Biology, 2020
The COVID‐19 pandemic caused by SARS‐CoV‐2 has been a global health challenge. Angiotensin‐converting enzyme 2 (ACE2) is the host receptor for SARS‐CoV‐2 entry.
Sanju Sinha, Kuoyuan Cheng, Alejandro A Schäffer, Kenneth Aldape, Eyal Schiff, Eytan Ruppin   +5 more
doaj   +1 more source

The Big Squeeze: A Social and Political History of the Controversial Mammogram [PDF]

, 2012
[Excerpt] The Big Squeeze: A Social and Political History of the Controversial Mammogram chronicles the often turbulent history of screening mammography since its introduction in the early 1970s. This book makes five key points.
Reynolds, Handel, MD
core   +2 more sources

Lessons learned from different prognostic factors analysis in intermediate-risk neuroblastoma: ten years’ experience at a tertiary center

Journal of the Egyptian National Cancer Institute
Background Intermediate-risk (IR) neuroblastoma represents a biologically and clinically diverse group of tumors. This study evaluates the feasibility of surgical excision and identifies prognostic factors that influence survival in IR-neuroblastoma ...
Mustafa Selim, Hanafy Hafez, Abeer M. Elsayed, Mohamed Shalaby, Abdalwahab R. Abdalwahab, Soad A. Eltokhy, Mohamed Fawzy   +6 more
doaj   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source