Results 21 to 30 of about 373,386 (221)

Heterogeneous clinicopathological findings and patient-reported outcomes in adults with MN1-altered CNS tumors: A case report and systematic literature review

Frontiers in Oncology, 2023
The uncommon MN1-altered primary central nervous system (CNS) tumors were recently added to the World Health Organization 2021 classification under the name Astroblastoma, MN1-altered. Another term used to describe them, “High-grade neuroepithelial tumor
Stephen C. Frederico, Stephen C. Frederico, Elizabeth Vera, Zied Abdullaev, Alvina Acquaye, Kenneth Aldape, Lisa Boris, Nicole Briceno, Anna Choi, Alexa Christ, Diane Cooper, Ewa Grajkowska, Tricia Kunst, Heather E. Leeper, Jason Levine, Jason Levine, Nicole Lollo, Drew Pratt, Martha Quezado, Ritu Shah, Kathleen Wall, Mark R. Gilbert, Terri S. Armstrong, Marta Penas-Prado   +23 more
doaj   +1 more source

Recommendations from a Dialogue on Evolving National Cancer Institute-Designated Comprehensive Cancer Center Community Outreach and Engagement Requirements: A Path Forward

Health Equity, 2021
While cancer mortality is declining in the United States, significant racial, ethnic, economic and geographic inequities persist. To help address inequities in cancer treatment, care, support and research, the National Cancer Institute (NCI) instituted ...
doaj   +1 more source

Mechanism of co-operation of mutant IL-7Rα and mutant NRAS in acute lymphoblastic leukemia: role of MYC

Haematologica, 2023
Acute lymphoblastic leukemia (ALL) is an aggressive leukemia which can be derived from either T-cell or B-cell precursors. With current treatments, the survival rate is high, but the treatments are highly toxic with severe side effects.
Hila Winer, Wenqing Li, Gisele Rodrigues, Tim Gower, Thomas Joshua Meyer, Julie Hixon, Scott K. Durum   +6 more
doaj   +1 more source

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Bailey H. H., Ballestrero A., Bellamy W. T., Betanzos-Lara S., Bozic I., Bushra Qamar, Carew J. S., Castonguay A., Chan J., Constantini P., Dai Y., Degterev A., Dindo D., Doroshow J. H., Dyke M. W. Van, Fagan V., Finnilä S., Frank J. E., Fu Y., Fu Y., Gaiddon C., Garbutcheon-Singh K. B., Hannon M. J., Hartinger C. G., Hileman E. A., Holbeck S., Huo H., Ian Hands-Portman, Isolda Romero-Canelón, Jessica M. Hearn, Jordan M. A., Jungwirth U., Kelland L., Kerr J. F., Kroemer G., Lazebnik Y. A., Liu Z., Liu Z., Liu Z., Lu J.-J., McKeage M. J., Millar A. W., Monneret C., Nagata S., Park G. Y., Paull K., Perchellet E. M., Peter J. Sadler, Petrelli A., Pittella F., Porteous C. M., Pracharova J., Purewal M., Rai S. S., Rixe O., Saraste A., Shoemaker R. H., Shoemaker R. H., Siddik Z., Sidler D., Tsutsui T., Türk D., Van den Bogert C., Zalacaín M., Zhang Y.-W., Zhe Liu, Zhou D.-F., Zhu Z.   +67 more
core   +1 more source

Evaluation of the frequency and pattern of local recurrence following intersphincteric resection for ultra-low rectal cancer

Journal of the Egyptian National Cancer Institute, 2014
Introduction: Abdomino-perineal resection has been the standard treatment for rectal tumors located ⩽5 cm from the anal verge. Recently, intersphincteric resection became a valid option which preserves the bowel continuity with better functional outcome.
W. Abdel-Gawad, A. Zaghloul, I. Fakhr, M. Sakr, A. Shabana, M. Lotayef, O. Mansour   +6 more
doaj   +1 more source

Prognostic value of CIP2A gene expression in adult Egyptian acute myeloid leukemia patients

Egyptian Journal of Medical Human Genetics, 2020
Background Protein phosphatase 2A (PP2A) functions as a tumor suppressor in many cancers. Cancerous inhibitor of protein phosphatase 2A (CIP2A) inhibits PP2A proteolytic degradation of c-Myc and enhances cell growth and tumor formation in several tissues.
Roxan E. Shafik, Azza M. Ibrahim, Fadwa Said, Naglaa M. Hassan, Hanan E. Shafik, Hala A. Shokralla   +5 more
doaj   +1 more source

Breast Cancer Vaccine: Are We There Yet? [PDF]

, 2012
In lieu of an abstract, here is the article\u27s first paragraph: Breast cancer is the most fatal form of cancer for female population worldwide. National Cancer Institute (NCI) estimates 226,870 females and 2,190 males to be diagnosed with breast cancer
Chablani, Lipika
core   +2 more sources

Her2/EGFR-PDGFR pathway aberrations associated with tamoxifen response in metastatic breast cancer patients

Journal of the Egyptian National Cancer Institute, 2022
Background Metastatic breast cancer (MBC) is a major health problem worldwide. Some patients improve on tamoxifen and others do not respond to treatment.
Ibrahim Malash, Osman Mansour, Rabab Gaafar, Sabry Shaarawy, Mona S. Abdellateif, Ola S. Ahmed, Abdel-Rahman N. Zekri, Abeer Bahnassy   +7 more
doaj   +1 more source

Successful use of whole genome amplified DNA from multiple source types for high-density Illumina SNP microarrays

BMC Genomics, 2018
Background The recommended genomic DNA input requirements for whole genome single nucleotide polymorphism microarrays can limit the scope of molecular epidemiological studies.
Casey L. Dagnall, Lindsay M. Morton, Belynda D. Hicks, Shengchao Li, Weiyin Zhou, Eric Karlins, Kedest Teshome, Salma Chowdhury, Kerrie S. Lashley, Joshua N. Sampson, Leslie L. Robison, Gregory T. Armstrong, Smita Bhatia, Gretchen A. Radloff, Stella M. Davies, Margaret A. Tucker, Meredith Yeager, Stephen J. Chanock   +17 more
doaj   +1 more source

Anti-cancer activity of phenyl and pyrid-2-yl 1,3-substituted benzo[1,2,4]triazin-7-ones and stable free radical precursors [PDF]

, 2018
Cell viability studies for benzo[1,2,4]triazin-7-ones and 1,2,4-benzotriazinyl (Blatter-type) radical precursors are described with comparisons made with 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO). All of the stable free radicals were several orders of
Andrey Berezin, Fawaz Aldabbagh, Georgia Zissimou, Harwood, Lee-Ann Keane, Martin Sweeney, Michael Carty, Panayiotis Koutentis, Styliana Mirallai   +8 more
core   +4 more sources