Results 101 to 110 of about 2,388,117 (306)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

LE RÔLE DE LA LANGUE DANS LA RECHERCHE DE L’IDENTITÉ NATIONALE [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2010
The role that was assigned to language in the search for identity varies considerably depending on the model of the nation adopted. It is precisely the „German” model, an organic model of nation, that dominates Russia nowadays.
Dr. Olga INKOVA
doaj  

Implementasi Pendidikan Karakter melalui Pembiasaan Menyanyikan Lagu Wajib Nasional pada Siswa Kelas Atas di SDM 21 Surakarta [PDF]

open access: yes, 2016
This study aims to describe: 1) Implementation of character education nationalism and national spirit through singing the national anthem in HR 21 Surakarta.
, Dra. Ratnasari Diah Utami, M.Si., M.Pd   +1 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Mapping Wilderness Character in Adams County, Pennsylvania

open access: yes, 2019
The spatial trends in wilderness character in Adams County, Pennsylvania were examined to evaluate how influenced specific areas are impacted by human activity and development.
Kaewwilai, Alyssa J
core  

Public Integrity, Economic Freedom and Governance Performance. A Comparative Study for the EU Member States and Acceding Countries [PDF]

open access: yes, 2010
The studies concerning the impact of corruption on the effectiveness of governance are numerous, valorising profound approaches, based on criteria and standards related to good governance, organizational behaviour.
Matei, Ani, Savulescu, Carmen.
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

The Welsh world in J. Wain's novel 'A Winter in the Hills'

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2018
This paper examines the image of the Welsh world in John Wain's novel “A Winter in the Hills” (1970). John Barrington Wain is a British writer, one of the founders of the “angry young men” movement.
Z.R. Zinnatullina, A.A. Khaibullina
doaj  

Islamic Identity: Its Reality and Traits in Ibn-Taimiya's Book Iqtidhaa' Assiraat Almustaqeem li Mukhaalafat Ass-haab Al-Jaheem [PDF]

open access: yesJournal of Islamic Studies, 2016
This paper studies the cultural aspect of Ibn-Taymiyah's well known book Iqtidhaa' Assiraat Almustaqeem li Mukhaalafat Ass-haab Al-Jaheem (Pursuit of the Straight Path Requires Unfollowing the Hellfire People).
Maha Jerais Al-Jerais
doaj  

Pembentukan Akhlak Anak Usia Dini Menurut Ibn Miskawaih [PDF]

open access: yes, 2013
: Early Childhood Character Building in the View of Ibn Miska- waih. During the reformation era, the national education system is apparently facing some problems. On the goal of national education, for instance, educational institutions have not achieved
Rosnita, R. (Rosnita)
core  

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