Results 71 to 80 of about 259,745 (261)

The Picture Storybook of Pancasila Values as the Formation of National Character in Pancasila and Civics Education Learning Class Five of Elementary School in Indonesia

Jurnal Teknologi Pendidikan
The Pancasila is five life principals of Indonesian and it has been crafted from the ancestor. The Indonesian independence fighters had been trying to create the Pancasila and now it is officially the Indonesian life principals.
Linda Zakiah, Komarudin, Eti Herawati
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

“THE BASIC PRINCIPLES OF OUR NATIONALITY” IN THE WORKS OF FYODOR BUSLAEV

Филологический класс, 2018
The purpose of this article is to give a general idea of the role of Fyodor Buslaev in formation and development of Russian philology. The author speaks about the innovative nature of Buslaev's understanding of the role of science as one of the most ...
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The Welsh world in J. Wain's novel 'A Winter in the Hills'

Ученые записки Казанского университета: Серия Гуманитарные науки, 2018
This paper examines the image of the Welsh world in John Wain's novel “A Winter in the Hills” (1970). John Barrington Wain is a British writer, one of the founders of the “angry young men” movement.
Z.R. Zinnatullina, A.A. Khaibullina
doaj  

LE RÔLE DE LA LANGUE DANS LA RECHERCHE DE L’IDENTITÉ NATIONALE [PDF]

Diversitate si Identitate Culturala in Europa, 2010
The role that was assigned to language in the search for identity varies considerably depending on the model of the nation adopted. It is precisely the „German” model, an organic model of nation, that dominates Russia nowadays.
Dr. Olga INKOVA
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Islamic Identity: Its Reality and Traits in Ibn-Taimiya's Book Iqtidhaa' Assiraat Almustaqeem li Mukhaalafat Ass-haab Al-Jaheem [PDF]

Journal of Islamic Studies, 2016
This paper studies the cultural aspect of Ibn-Taymiyah's well known book Iqtidhaa' Assiraat Almustaqeem li Mukhaalafat Ass-haab Al-Jaheem (Pursuit of the Straight Path Requires Unfollowing the Hellfire People).
Maha Jerais Al-Jerais
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source