Results 41 to 50 of about 138,913 (312)

Is vaccine type seropositivity a marker for human papillomavirus vaccination? National Health and Nutrition Examination Survey, 2003–2010

International Journal of Infectious Diseases, 2015
Objective: Since 2006, human papillomavirus (HPV) vaccination has been routinely recommended for adolescent females in the USA. The quadrivalent vaccine induces long-term seropositivity to HPV 6/11/16, which may be useful as a marker for HPV vaccine ...
Emiko Y. Petrosky, Susan Hariri, Lauri E. Markowitz, Gitika Panicker, Elizabeth R. Unger, Eileen F. Dunne   +5 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Risk Factors for Stroke Based on the National Health and Nutrition Examination Survey

The Journal of nutrition, health and aging, 2020
To explore the risk factors for stroke by using National Health and Nutrition Examination Survey (NHANES).A total of 19384 cases from the NHANES database during 2005 to 2016 were included in this study, of which 661 were stroke patients, with a weighted prevalence of 2.60%.
Mai, X., Liang, Xingmin
openaire   +2 more sources

Lipids and Pulmonary Function in the Third National Health and Nutrition Examination Survey [PDF]

American Journal of Epidemiology, 2002
Studies considering the association between total cholesterol and noncardiovascular mortality, particularly from respiratory disease, yield inconclusive findings. To explore this question, the relation of lipids to pulmonary function, specifically forced expiratory volume in 1 second (FEV(1)), was investigated in the Third National Health and Nutrition
Dominic J, Cirillo, Yuri, Agrawal, Patricia A, Cassano   +2 more
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Oral Health And Anxiety: Evidence From Genetics And Nhanes

International Dental Journal
Aim or purpose: This study aimed to investigate the potential causal link between oral health and anxiety using data from NHANES and Mendelian Randomization, addressing the gap highlighted in recent literature (Pi Y, Jiao Z, Wang L. J Affect Disord. 2024;
Zeng Lijun, Liu Jinsong
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The associations between the Geriatric Nutritional Risk Index and all-cause, cancer-specific, and cardiovascular mortality in the U.S. population: a large-scale pooled survey

Nutrition & Metabolism
Background Previous studies have reported a close association between the Geriatric Nutritional Risk Index (GNRI) and various conditions. However, the association between the GNRI and mortality remains unclear. To examine the correlation between the GNRI
Kun Han, Tianhong Wang, Congcong Zou, Tao Li, Leng Zhou   +4 more
doaj   +1 more source

Association of Hypoalbuminemia With Osteoporosis: Analysis of the National Health and Nutrition Examination Survey [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2016
The association of hypoalbuminemia with osteoporosis in human studies is controversial.We tested the independent association between hypoalbuminemia and osteoporosis in a national dataset.This is a cross-sectional observation.Participants are individuals selected from the National Health and Nutrition Examination Survey (NHANES) with available clinical,
Farsad, Afshinnia, Subramaniam, Pennathur   +1 more
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source