Results 131 to 140 of about 794,929 (256)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Occupational health education and training as a sustainable development goal. [PDF]

Front Public Health
Siegrist J, Bollmann U, Moyo D.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Broadening participation: 20-year outcomes from undergraduate science training programs. [PDF]

Sci Adv
Woodcock A, Aguilar SD, Hernandez PR, Peterson ME, Schultz PW.   +4 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Comparisons of core component delivery in cardiac rehabilitation programs by country income classification and decade based on the 2025 Global Audit Update: A survey study. [PDF]

PLoS Med
Ghisi GLM, Carson RP, Turk Adawi K, Ding R, Mampuya WM, Jiandani MP, Martinez J, Cruz Rivero M, Anchique CV, van Schalkwijk DL, Gallagher J, Akinci B, Candelaria D, Champaiboon J, Quesada-Chaves DF, Norekvål TM, Szadkowska I, Jug B, Kouidi E, Supervia M, Kim WS, Mettananda C, Mbau L, Aimakova GT, Grace SL, ICCPR Global Cardiac Rehabilitation Audit Update Investigators.   +25 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Care at doorstep for psychiatric disorders by community volunteers: Readiness to volunteer for community mental health-qualitative study among nursing students. [PDF]

J Educ Health Promot
Govindan R, Vilson A, Komala TY, Pooja, Balamurugan G, Gouda VB, Rajani P, Manjunatha N, Kumar CN, Math SB.   +9 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Evolution of the Healthcare System in Saudi Arabia Over the Last Century: A Historical and Policy Analysis. [PDF]

J Healthc Leadersh
Sheerah HA, Alzaaqi SM, Arafa A, Banjar WM, Liu K, Withers M, El-Jardali F, Penttinen P, Al-Jedai AH, Selbie D.   +9 more
europepmc   +1 more source