Results 121 to 130 of about 32,707,685 (254)

New dimensions in mental health.

"Report from the director, National Institute of Mental Health."Mode of access ...
National Institute of Mental Health (U.S.)
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Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Competency-Based Health Professions Education in Evolution: Challenges and Adaptations After Implementation. [PDF]

Perspect Med Educ
Englander R, Goldhamer ME, Chen AMH, Oswald A, Atkinson A, Caretta-Weyer H, Chan TM, Chou FC, Dalseg TR, Kini RG, Ladenheim RI, Niemi-Murola L, Turner DA, Snell L, Hall AK, As members of the International Competency-Based Health Professions Educators Collaborative.   +15 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Meeting report of the fifth symposium organized by the coalition to strengthen the HPV immunization community (CHIC): Nairobi, Kenya - advancing sustainable HPV vaccination programs in Africa. [PDF]

BMC Proc
Bolio A, Jennings MC, Burdier R, Jindal S, Kagan S, Karafillakis E, Chaurat E, Njoh AA, Amponash-Dacosta E, Guemgo S, Bakouan RD, Njie M, Jalang'o RE, Wangeci C, Njogu RN, Ndiaye A, Mashiringo C, Morgan C, Vorsters A, Waheed DE.   +19 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Implementing single-dose HPV vaccination in Canada. [PDF]

Hum Vaccin Immunother
Leggatt M, Moothathamby N, Dubé È, Shapiro GK.   +3 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

NIOSH extramural research and training program\u2028: annual report of fiscal year 2012

This report contains a description of the NIOSH extramural research and training programs that were active during FY2012 and information on the structure and function of the OEP.

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