Results 101 to 110 of about 32,707,685 (254)
NATIONAL "E-EXTENSION" PROGRAMS: FEASIBILITY AND STRUCTURE [PDF]
Illinois agriculture and natural resource e-Extension programs have exceeded expectations. National e-Extension programs will also succeed given they explicitly help clients make decisions, make available user-friendly decision tools and data, use GIS ...
White, Carolyn +2 more
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
x, 30 p.This operational handbook supports country-led contextualization and implementation of the World Health Organization’s roadmap on national workforce capacity for essential public health functions (EPHFs). Developed in response to lessons from the
World Health Organization
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Health, United States spotlight : health status and determinants [PDF]
Health, United States is the annual report on health, produced by the National Center for Health Statistics and submitted by the Secretary of the Department of Health and Human Services to the President and Congress.The report uses data from government ...
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
, 1969 No. 1-5 issued as Public Health Service publication, no. 1860, etc.; no. 6-12 issued as DHEW publication no.
National Institute of Mental Health (U.S.) +1 more
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Interaction effects of a child tax credit, national health insurance, and assured child support [PDF]
If the government offered a refundable tax credit for children, national health insurance, and an assured child support benefit to all families with children - poor families as well as nonpoor families - what would happen to poverty, welfare dependency ...
D. R. Meyer, R. Y. Kim, I. Garfinkel
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source