Results 41 to 50 of about 2,782,757 (302)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Integrating oral pre-exposure prophylaxis delivery in primary care family planning clinics: a pragmatic, stepped-wedge, cluster-randomised trial

The Lancet Primary Care
Summary: Background: Integrating pre-exposure prophylaxis (PrEP) delivery in family planning settings might offer an efficient platform to reach women at increased risk for HIV. This study aimed to prospectively assess the effectiveness of a health-care
Kenneth K Mugwanya, MBChB, Daniel Matemo, MPH, Allison Meisner, PhD, Torin Schaafsma, MS, Jennifer Morton, MPH, Cynthia Wandera, BSN, Valarie Kemunto, BSN, Irine Cherotich, MSc, Stephen Odhiambo, Dip, Mercy Bii, Dip, Beatrice Oduor, Dip, Esther Achieng, Dip, Tecy Oyombra, Dip, David Owaga, BSc, Kristin M Beima-Sofie, PhD, ProfMD Jared M Baeten, PhD, John Kinuthia, MMed   +16 more
doaj   +1 more source

Estimation of bed net coverage indicators in Tanzania using mobile phone surveys: a comparison of sampling approaches

Malaria Journal, 2022
Background Threats to maintaining high population access with effective bed nets persist due to errors in quantification, bed net wear and tear, and inefficiencies in distribution activities. Monitoring bed net coverage is therefore critical, but usually
Matt Worges, Benjamin Kamala, Joshua Yukich, Frank Chacky, Samwel Lazaro, Charles Dismas, Sijenun Aroun, Raya Ibrahim, Mwinyi Khamis, Mponeja P. Gitanya, Deodatus Mwingizi, Hannah Metcalfe, Willhard Bantanuka, Sena Deku, David Dadi, Naomi Serbantez, Dana Loll, Hannah Koenker   +17 more
doaj   +1 more source

What are the Proven Financial Benefits of Health and Wellness Programs? [PDF]

, 2014
The implementation and growth of Health & Wellness programs has become a very hot topic for companies seeking to obtain maximum returns on their health investment dollars. According to a 2011 PwC Health and Well-being Touchstone Survey of approximately 1,
Chow, Joy, Stahno, John
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

County and City Health Departments: The Need for Sustainable Funding and the Potential Effect of Health Care Reform on Their Operations [PDF]

, 2009
Outlines the role of local health departments, the impact of funding cuts on staff, programs, and services, and the implications for public health.
Jack A. Meyer, Lori Weiselberg
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Creating Lasting Comprehensive School Health Programs: The Connection Between Health and Achievement [PDF]

, 1999
Student health has a profound effect upon student academic performance. In 1994, with a focus on increasing student achievement, the Public Education Network (PEN) began working with the Centers for Disease Control and Prevention, Division of Adolescent ...

core  

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

Community acceptance and implementation of HIV prevention interventions for injection drug users [PDF]

, 2002
In 1997, the National Institutes of Health (NIH) reviewed evidence of the effectiveness of HIV prevention programs for injection drug users (IDUs) and recommended that three types ofinterventions be implemented to prevent transmission of HIV among IDUs ...
Brian R. Edlin, Courtney McKnight, Don C. Des Jarlais, Karen Vernon, Moher Downing, Nina Mulia, Thomas H. Riess   +6 more
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