Results 61 to 70 of about 846,596 (305)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

National Health Interview Survey [PDF]

The National Health Interview Survey (NHIS) provides information on the health of the U.S. civilian noninstitutionalized population through confidential interviews conducted in households.

core   +2 more sources

Needs assessment for national wildlife health programs

One Health
Wildlife health programs are essential for monitoring and managing wildlife populations, which in turn supports biodiversity, ecosystem stability, the economy, and public health.
Liz P. Noguera Z., Jonathan M. Sleeman, Richard Muvunyi, Sarin Suwanpakdee, Anuwat Wiratsudakul, Nareerat Sangkachai, Sarah H. Olson, Mathieu Pruvot   +7 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Public Private Partnership for Equitable Provision of Quality Health Services [PDF]

, 2005
This report presents the findings of an independent Technical Review that focused on the promotion of Public Private Partnership (PPP) for equitable provision of quality health services in Tanzania.
Health Research for Action, (HERA)
core  

Patient preferences for long-acting antiretroviral treatment among people with HIV in Kenya: a discrete choice experiment

BMC Infectious Diseases
Background For people with HIV (PWH), long-acting antiretroviral therapies (LA-ART) are promising treatment alternatives to daily oral regimens, with potential to improve adherence and achieve viral suppression.
Jacinda Tran, Enrique M. Saldarriaga, Anne Kaggiah, Catherine Maina, Naum Jepkosgei, Elizabeth Mwangi, Douglas Barthold, Brett Hauber, Jane M. Simoni, John Kinuthia, Susan M. Graham   +10 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Impact of the use of the ultra-portable digital x-ray with CAD4TB for active case finding for tuberculosis in Nigeria

Frontiers in Digital Health
BackgroundThe ultra-portable digital x-ray (UPDX) with computer-aided detection (CAD) is a new technology aimed at bringing tuberculosis (TB) screening innovations to hard-to-reach communities and strengthening the active case-finding (ACF) interventions
Abiola Alege, Sani Useni, Austin Ihesie, Austin Ihesie, Rupert Eneogu, Rupert Eneogu, Aderonke Agbaje, Bethrand Odume, Debby Nongo, Eze Chukwu, Chidubem Ogbudebe, Omosalewa Oyelaran, Chris Anyomi, Samuel Akingbesote, Zhi Zhen Qin, Rachael Barrett, Obioma Chijioke-Akaniro, Obioma Chijioke-Akaniro, Chukwuma Anyaike, Chukwuma Anyaike, Atana Ewa, Atana Ewa   +21 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source